Escherichia coli strain KCJK8755

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8755 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic, thriving optimally at 37°C within a mesophilic temperature range. Its cellular arrangement includes pairs and singles, and it possesses flagella, indicating motility. This strain has a single replicon and is characterized by a double membrane structure. E. coli KCJK8755 is host-associated, exhibiting a free-living biotic relationship. It has a diverse range of potential hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other mammals, birds, and even plants such as Solanum lycopersicum (tomatoes) and Brassica oleracea var. italica (broccoli). This wide host range highlights its ecological versatility and adaptability. The strain is associated with numerous health effects, particularly in humans, where it can cause urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and more severe conditions such as septicemia and hemolytic uremic syndrome (HUS). Its pathogenicity is predominantly recognized in human hosts, making it a significant concern in medical microbiology. The ecological presence of E. coli KCJK8755 in various hosts underscores its role in both health and disease, emphasizing the importance of monitoring this strain in clinical and environmental settings. Its ability to inhabit diverse environments and cause a range of diseases illustrates the complex interactions between microorganisms and their hosts, highlighting the need for ongoing research into its pathogenic mechanisms and ecological impacts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8755

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8755
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8755 NODE_269_length_200_cov_7.890411,

Gene Summary

Adenine Count

1203019 bp

Thymine Count

1200214 bp

Guanine Count

1221616 bp

Cytosine Count

1233508 bp

Genome Length

4858357 bp

Protein-coding Genes

4520 genes

Non-Coding Genes

352 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
formate hydrogenlyase transcriptional activator flhaFIC27_04760Not AvailableNegative1000972 - 100305078419.5
hydrogenase maturation carbamoyl dehydratase hypeFIC27_04765Not AvailableNegative1003124 - 100413435124.6
hydrogenase formation protein hypdFIC27_04770Not AvailableNegative1004131 - 100525241393.7
hydrogenase 3 maturation protein hypcFIC27_04775Not AvailableNegative1005252 - 10055249732.58
hydrogenase nickel incorporation protein hypbFIC27_04780Not AvailableNegative1005515 - 100638731566.8
hydrogenase maturation nickel metallochaperone hypaFIC27_04785Not AvailableNegative1006391 - 100674113168.9
hypothetical proteinFIC27_04790Not AvailablePositive1006647 - 10068658011.78
formate hydrogenlyase regulator hycaFIC27_04795Not AvailablePositive1006953 - 100741417627.9
4fe-4s dicluster domain-containing proteinFIC27_04800Not AvailablePositive1007539 - 100815021874.4
formate hydrogenlyase subunit 3FIC27_04805Not AvailablePositive1008147 - 100997364127.2

Displaying genes 1191 – 1200 of 4872 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total