Escherichia coli strain KCJK8767

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8767 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe. It exhibits mobility and possesses flagella, which allows for movement in various environments. With an optimal growth temperature of 37°C, it falls within the mesophilic temperature range, indicating it thrives in moderate temperature conditions typical of warm-blooded hosts. This strain is host-associated and can be found in diverse biotic relationships, primarily as a free-living organism. It has a notable range of hosts, including Homo sapiens, various livestock (such as Gallus gallus and Bos taurus), other mammals like Canis lupus familiaris and Felis catus, as well as non-mammalian species like Apis mellifera and Solanum lycopersicum. This wide host range suggests a significant ecological adaptability. KCJK8767 is associated with numerous health effects, particularly in humans, where it can lead to conditions such as urinary tract infections (UTIs), gastrointestinal infections, and even severe outcomes like hemorrhagic colitis and hemolytic uremic syndrome (HUS). The strain is linked to various health complications, ranging from mild diarrhea to serious conditions like neonatal meningitis and septicemia. The diverse pathogenic potential of E. coli strain KCJK8767 highlights its ecological role in both human health and disease. Its ability to inhabit multiple hosts and cause a range of infections underscores the importance of monitoring such strains in both clinical and environmental contexts to mitigate public health risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8767

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8767
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8767

Gene Summary

Adenine Count

1141735 bp

Thymine Count

1148770 bp

Guanine Count

1178331 bp

Cytosine Count

1184453 bp

Genome Length

4653289 bp

Protein-coding Genes

4445 genes

Non-Coding Genes

185 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
copper-exporting p-type atpase copaFIC29_05745Not AvailableNegative1193038 - 119554287864.3
glutaminase aFIC29_05750Not AvailablePositive1195804 - 119673632988.3
amino acid permeaseFIC29_05755Not AvailablePositive1196739 - 119803145661.5
hth-type transcriptional regulator cuerFIC29_05760Not AvailablePositive1198156 - 119856315236.0
nfed family proteinFIC29_05765Not AvailableNegative1198564 - 119902216939.8
spfh/band 7/phb domain proteinFIC29_05770Not AvailableNegative1199019 - 119993633745.1
iron abc transporter atp-binding protein fetaFIC29_05775Not AvailablePositive1200082 - 120075925386.4
iron export abc transporter permease subunit fetbFIC29_05780Not AvailablePositive1200746 - 120152528166.5
chaperedoxinFIC29_05785Not AvailableNegative1201588 - 120244231762.9
nadp(+)-dependent aldehyde reductaseFIC29_05790Not AvailableNegative1202503 - 120331229412.0

Displaying genes 1221 – 1230 of 4630 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total