Escherichia coli strain KCJK8798

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8798 is a facultative anaerobic, Gram-negative bacterium characterized by its rod shape and mobility, facilitated by the presence of flagella. This strain typically exists in pairs or singles and thrives optimally at 37°C, placing it within the mesophilic temperature range. It possesses a single replicon and has a dual membrane structure, which is typical for Gram-negative organisms. KCJK8798 is primarily host-associated, demonstrating a free-living biotic relationship with a wide array of hosts including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), various mammals, and even some plants such as Solanum lycopersicum (tomatoes) and Brassica oleracea var. italica (broccoli). The strain is implicated in numerous health effects, particularly in humans, where it can cause urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The diverse host range of strain KCJK8798 underscores its ecological versatility and adaptability. This adaptability may contribute to its pathogenic potential in various environments, highlighting the importance of monitoring E. coli strains in both clinical settings and agricultural contexts. The strain’s ability to inhabit multiple hosts and cause significant health issues suggests that it plays a critical role in the dynamics of infectious disease transmission and public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8798

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8798
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8798

Gene Summary

Adenine Count

1156471 bp

Thymine Count

1157353 bp

Guanine Count

1200358 bp

Cytosine Count

1201446 bp

Genome Length

4715725 bp

Protein-coding Genes

4323 genes

Non-Coding Genes

259 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase foldFIB81_12740Not AvailablePositive2671644 - 267251031015.6
ribosome-associated protein ybcjFIB81_12745Not AvailablePositive2672512 - 26727247389.95
metal-dependent hydrolaseFIB81_12750Not AvailablePositive2672832 - 267335319483.5
cysteine--trna ligaseFIB81_12755Not AvailableNegative2673389 - 267477452186.9
peptidylprolyl isomerase bFIB81_12760Not AvailablePositive2674948 - 267544218168.5
udp-2,3-diacylglucosamine diphosphataseFIB81_12765Not AvailablePositive2675445 - 267616726925.8
5-(carboxyamino)imidazole ribonucleotide mutaseFIB81_12770Not AvailablePositive2676285 - 267679417781.3
5-(carboxyamino)imidazole ribonucleotide synthaseFIB81_12775Not AvailablePositive2676791 - 267785839479.4
carbamate kinaseFIB81_12780Not AvailableNegative2677995 - 267888831659.1
duf2877 domain-containing proteinFIB81_12785Not AvailableNegative2678885 - 267970029685.9

Displaying genes 2671 – 2680 of 4582 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total