Escherichia coli strain KCJK8826

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8826 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. This strain is motile and possesses flagella, facilitating movement within its host-associated habitat. KCJK8826 has an optimal growth temperature of 37°C and falls within the mesophilic temperature range. It is characterized by having a single replicon and two membranes. This strain has a wide array of biotic relationships, being free-living and associated with numerous hosts, including Homo sapiens, Gallus gallus, Bos taurus, and various other vertebrates and invertebrates. Notably, it has been linked to a variety of health effects, particularly in humans, where it is known to cause urinary tract infections (UTIs), peritonitis, gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The presence of KCJK8826 in diverse hosts suggests its ecological versatility and potential for transmission across species. Its pathogenicity primarily affects humans, underlining the importance of monitoring this strain in clinical and environmental contexts. The strain's role in causing significant health issues, particularly gastrointestinal and urinary tract infections, highlights the need for ongoing research into its mechanisms of pathogenesis and its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8826

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8826
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8826 NODE_519_length_200_cov_9.767123,

Gene Summary

Adenine Count

1155952 bp

Thymine Count

1161507 bp

Guanine Count

1195107 bp

Cytosine Count

1202670 bp

Genome Length

4715236 bp

Protein-coding Genes

4544 genes

Non-Coding Genes

212 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme- a synthaseFIC35_01950Not AvailablePositive386018 - 38689631646.4
citrate/succinate antiporter cittFIC35_01955Not AvailablePositive386947 - 38841053095.7
ribonuclease iFIC35_01960Not AvailablePositive388524 - 38933029614.1
nucleoside diphosphate kinase regulatorFIC35_01965Not AvailablePositive389560 - 38997014928.0
glutathione-dependent formaldehyde dehydrogenaseFIC35_01970Not AvailableNegative390201 - 39143944243.3
universal stress protein uspgFIC35_01975Not AvailablePositive391660 - 39208815937.1
alkyl hydroperoxide reductase subunit fFIC35_01980Not AvailableNegative392209 - 39377456180.4
alkyl hydroperoxide reductase subunit cFIC35_01985Not AvailableNegative393903 - 39446620762.5
thiol:disulfide interchange protein dsbgFIC35_01990Not AvailablePositive394838 - 39558427485.5
lysr family transcriptional regulatorFIC35_01995Not AvailablePositive395793 - 39669534298.8

Displaying genes 531 – 540 of 4756 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total