Escherichia coli strain KCJK8829

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8829 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and exhibits mobility due to its flagella. This strain is primarily host-associated and demonstrates a free-living biotic relationship. It is mesophilic with an optimal growth temperature of 37°C. KCJK8829 has a single replicon and is characterized by having two membranes. This strain is associated with a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and various other vertebrates and invertebrates. Such a diverse host range indicates its ecological versatility and potential for interaction with different organisms in various environments. E. coli strain KCJK8829 is notably pathogenic to humans, being linked to several health effects. It has been implicated in urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions like neonatal meningitis and hemolytic uremic syndrome (HUS). The strain's role in these diseases highlights its potential impact on public health and underscores the importance of monitoring and understanding its pathogenicity. The presence of E. coli strain KCJK8829 in diverse habitats and its association with a variety of hosts suggest that it plays a significant role in both human health and disease dynamics. This highlights the need for continuous research into its pathogenic mechanisms and ecological presence, given its implications for zoonotic transmission and food safety.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8829

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8829
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8829

Gene Summary

Adenine Count

1162164 bp

Thymine Count

1162852 bp

Guanine Count

1211230 bp

Cytosine Count

1194538 bp

Genome Length

4730784 bp

Protein-coding Genes

4311 genes

Non-Coding Genes

282 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphatidate cytidylyltransferaseFIB34_11870Not AvailableNegative2454450 - 245534633279.0
cdp-alcohol phosphatidyltransferase family proteinFIB34_11875Not AvailableNegative2455346 - 245595122654.6
pyridoxine 4-dehydrogenaseFIB34_11885Not AvailableNegative2458490 - 245935030707.8
phenylacetic acid degradation protein paayFIB34_11890Not AvailableNegative2459581 - 246017121441.0
phenylacetic acid degradation operon negative regulatory protein paaxFIB34_11895Not AvailableNegative2460153 - 246110335284.6
phenylacetate--coa ligaseFIB34_11900Not AvailableNegative2461204 - 246251748969.8
3-oxoadipyl-coa thiolaseFIB34_11905Not AvailableNegative2462544 - 246374942279.2
hydroxyphenylacetyl-coa thioesterase paaiFIB34_11910Not AvailableNegative2463749 - 246417114851.6
3-hydroxyacyl-coa dehydrogenase paacFIB34_11915Not AvailableNegative2464161 - 246558851706.6
2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-coa isomeraseFIB34_11920Not AvailableNegative2465590 - 246637828438.3

Displaying genes 2501 – 2510 of 4593 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4798 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4798 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total