Escherichia coli strain KCJK8887

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8887 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and exhibits mobility due to the presence of flagella. This strain thrives optimally at 37°C and falls within the mesophilic temperature range. It is characterized by a unique habitat association with various hosts, including Homo sapiens, Gallus gallus, Bos taurus, and multiple other vertebrates and invertebrates. The bacterium forms arrangements in pairs or singles and possesses a single replicon and two membranes. As a free-living organism, E. coli strain KCJK8887 interacts with a diverse array of host species, which may contribute to its pathogenic potential. It is known to cause a wide range of health effects in humans, including urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The extensive list of diseases associated with this strain underscores its pathogenicity and the public health significance it holds. Ecologically, the ability of E. coli strain KCJK8887 to colonize various hosts suggests a complex biotic relationship, allowing for its survival and propagation in diverse environments. This adaptability may facilitate the transmission of virulence factors across different species, thereby influencing the epidemiology of infections linked to this strain. Understanding the interactions between E. coli KCJK8887 and its numerous hosts can provide insights into controlling the spread of associated diseases.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8887

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8887
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8887 NODE_787_length_210_cov_5.421687,

Gene Summary

Adenine Count

1129785 bp

Thymine Count

1128887 bp

Guanine Count

1184966 bp

Cytosine Count

1186536 bp

Genome Length

4630174 bp

Protein-coding Genes

4472 genes

Non-Coding Genes

214 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
septum formation inhibitor mafFIB35_01980Not AvailablePositive426335 - 42691921692.1
23s rrna pseudouridine(955/2504/2580) synthase rlucFIB35_01985Not AvailableNegative427031 - 42799036028.7
ribonuclease eFIB35_01990Not AvailablePositive428563 - 431638114493.0
transcription termination/antitermination protein nusgFIB35_01995Not AvailablePositive431639 - 4318899135.82
50s ribosomal protein l11FIB35_02000Not AvailablePositive432048 - 43247614876.2
50s ribosomal protein l1FIB35_02005Not AvailablePositive432480 - 43318424731.1
50s ribosomal protein l10FIB35_02010Not AvailablePositive433597 - 43409417712.6
50s ribosomal protein l7/l12FIB35_02015Not AvailablePositive434161 - 43452612295.8
dna-directed rna polymerase subunit betaFIB35_02020Not AvailablePositive434846 - 438874150641.0
dna-directed rna polymerase subunit beta'FIB35_02025Not AvailablePositive438951 - 443174155169.0

Displaying genes 531 – 540 of 4686 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total