Escherichia coli strain KCJK8899

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain KCJK8899 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic oxygen requirement. This strain is characterized by its mobility, facilitated by the presence of flagella, and typically exists in pairs or as single cells. It thrives optimally at 37°C and falls within the mesophilic temperature range. E. coli KCJK8899 is found in host-associated habitats and has a diverse range of hosts, including Homo sapiens, various livestock such as Bos taurus and Sus scrofa, as well as numerous other vertebrates and invertebrates, such as Apis mellifera and Solanum lycopersicum. Its biotic relationship is classified as free-living, indicating its ability to survive independently within its environment. The strain is associated with a wide array of health effects, primarily affecting humans and animals. It is linked to urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as septicemia and neonatal meningitis. Other health concerns include foodborne infections, colibacillosis, and complications like hemolytic uremic syndrome (HUS) and chronic mastitis. The pathogenicity of E. coli KCJK8899 underscores its significance in both clinical and ecological contexts, particularly concerning its interaction with human and animal hosts. Its ability to cause a variety of infections highlights the need for continued research and monitoring of E. coli strains in relation to public health and food safety. Understanding its host associations may provide insights into transmission dynamics and potential preventive measures against infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain KCJK8899

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain KCJK8899
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain KCJK8899

Gene Summary

Adenine Count

1165646 bp

Thymine Count

1167467 bp

Guanine Count

1202229 bp

Cytosine Count

1208170 bp

Genome Length

4743512 bp

Protein-coding Genes

4268 genes

Non-Coding Genes

322 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ribosome silencing factorFIB30_12435Not AvailableNegative2606690 - 260700711582.9
adenosylcobalamin/alpha-ribazole phosphataseFIB30_12440Not AvailableNegative2607267 - 260787823318.8
nicotinate-nucleotide adenylyltransferaseFIB30_12445Not AvailableNegative2607902 - 260854324529.3
dna polymerase iii subunit deltaFIB30_12450Not AvailableNegative2608545 - 260957638702.0
lps assembly lipoprotein lpteFIB30_12455Not AvailableNegative2609576 - 261015721357.8
leucine--trna ligaseFIB30_12460Not AvailableNegative2610172 - 261275497241.0
zinc ribbon-containing proteinFIB30_12465Not AvailablePositive2612989 - 261347118798.2
sel1-like repeat proteinFIB30_12470Not AvailableNegative2613541 - 261451837120.8
duf1266 domain-containing proteinFIB30_12475Not AvailablePositive2614682 - 261538927793.6
j domain-containing proteinFIB30_12480Not AvailablePositive2615386 - 261681355265.4

Displaying genes 2671 – 2680 of 4590 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total