Klebsiella pneumoniae subsp. pneumoniae strain UCO-490

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae subsp. pneumoniae strain UCO-490 is a Gram-negative, rod-shaped bacterium that is classified as a chemoheterotroph, meaning it derives its energy from organic compounds. This strain typically exists in a host-associated habitat, indicating a close relationship with its host organisms. It is characterized by a variety of cell arrangements, including chains, pairs, and singles, and possesses flagella, which contribute to its mobility. UCO-490 is a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. Its optimal growth temperature is 37°C, placing it in the mesophilic range, which is conducive for growth in warm-blooded hosts. The strain contains a single replicon and is structured with two membranes, a typical feature of Gram-negative bacteria. In terms of health impacts, Klebsiella pneumoniae subsp. pneumoniae strain UCO-490 is known to be associated with pneumonia, particularly community-acquired pneumonia (CAP), posing a significant risk in clinical settings. The bacterium is nonsporulating, which means it does not form spores as a means of survival under adverse conditions. From an ecological perspective, the free-living nature of this strain suggests it may play a role in microbial communities within its host environments. Its ability to cause disease, combined with its diverse cell arrangements and mobility, underscores the importance of monitoring Klebsiella pneumoniae in both clinical and ecological studies to understand its behavior and impact on health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainsubsp. pneumoniae strain UCO-490

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae subsp. pneumoniae strain UCO-490
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Klebsiella pneumoniae subsp. pneumoniae strain UCO-490

Gene Summary

Adenine Count

1285538 bp

Thymine Count

1290463 bp

Guanine Count

1688271 bp

Cytosine Count

1681999 bp

Genome Length

5946271 bp

Protein-coding Genes

5667 genes

Non-Coding Genes

358 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
acetolactate synthase small subunitFHQ31_17060Not AvailablePositive3430087 - 343037410884.3
transcriptional regulator uhpaFHQ31_17065Not AvailablePositive3430525 - 343111821075.8
signal transduction histidine-protein kinase/phosphatase uhpbFHQ31_17070Not AvailablePositive3431115 - 343261755717.7
mfs transporterFHQ31_17075Not AvailablePositive3432629 - 343395748246.0
hexose-6-phosphate:phosphate antiporterFHQ31_17080Not AvailablePositive3434103 - 343549450625.4
duf1198 family proteinFHQ31_17085Not AvailablePositive3435631 - 343608317328.0
dna-binding transcriptional regulatorFHQ31_17090Not AvailableNegative3436213 - 343653611714.3
type ii toxin-antitoxin system rele/pare family toxinFHQ31_17095Not AvailableNegative3436520 - 343687913839.6
purine ribonucleoside efflux pump nepiFHQ31_17100Not AvailablePositive3437090 - 343828341633.4
phosphonoacetaldehyde hydrolaseFHQ31_17105Not AvailableNegative3438280 - 343908928743.4

Displaying genes 3511 – 3520 of 6025 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC475056
Community-acquired pneumonia (cap)CausesPMC7609860

Displaying health effects 1 – 2 of 2 in total