Klebsiella pneumoniae strain hu585

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain hu585 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, relying on chemoheterotrophic processes for energy. This organism is typically found in host-associated environments and can exist in various arrangements, including chains, pairs, and singles. It possesses flagella, which contribute to its mobility, and has a mesophilic optimal growth temperature of 37°C. This strain is significant in clinical microbiology due to its wide array of pathogenic effects on human health. Klebsiella pneumoniae strain hu585 is known to cause bacteremia, urinary tract infections, pneumonia, and a range of other serious conditions such as meningitis, liver abscesses, and sepsis. It has also been implicated in infections across various hosts, including mammals, birds, and other metazoans, indicating a complex biotic relationship with multiple species. The ability of K. pneumoniae to thrive in diverse environments and cause infections in multiple hosts highlights its ecological versatility and potential for pathogenicity. This adaptability may pose challenges for treatment and control measures in both human and veterinary medicine, emphasizing the importance of continued surveillance and research on this strain and its interactions within various ecosystems. The presence of a single replicon and two membranes is characteristic of this bacterium, which may play a role in its survival and pathogenic mechanisms.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain hu585

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain hu585
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain hu585

Gene Summary

Adenine Count

1128452 bp

Thymine Count

1124093 bp

Guanine Count

1505374 bp

Cytosine Count

1532156 bp

Genome Length

5290075 bp

Protein-coding Genes

4961 genes

Non-Coding Genes

99 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
alpa family phage regulatory proteinFHD50_11890Not AvailableNegative2470365 - 24706079701.73
AttrNot AvailableNot AvailablePositive2470648 - 2470659Not Available
Transcriptional regulatorFHD50_11895Not AvailableNegative2470667 - 24708858614.7
IntegraseFHD50_11900Not AvailableNegative2470878 - 247211347849.5
Putative large terminase subunitFHD50_11905Not AvailableNegative2472279 - 247292324371.3
Putative small terminase subunitFHD50_11910Not AvailableNegative2472923 - 247335715585.8
Gp62FHD50_11915Not AvailableNegative2473605 - 247403615338.0
Gp61FHD50_11920Not AvailableNegative2474033 - 247435611960.2
Gp60FHD50_11925Not AvailableNegative2474308 - 247467013871.4
hypothetical proteinFHD50_11930Not AvailablePositive2474997 - 24752218602.42

Displaying genes 41 – 50 of 5060 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total