Klebsiella pneumoniae strain KP95

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain KP95 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and chemoheterotroph. This strain demonstrates a versatile cell arrangement, existing in chains, pairs, and singles, and exhibits mobility due to the presence of flagella. KP95 thrives optimally at 37°C and is categorized as mesophilic, indicating its preference for moderate temperature ranges. This bacterium is host-associated and has a broad spectrum of biotic relationships, being free-living in various environments. It has been identified in multiple hosts, including Homo sapiens, Gallus gallus, and other metazoans such as Danio rerio and Sus scrofa. The pathogenicity of KP95 is significant, as it is linked to numerous health effects in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis. Other notable conditions associated with this strain include intra-abdominal infections, liver abscesses, and neonatal sepsis. Klebsiella pneumoniae strain KP95 is nonsporulating and possesses a single replicon along with a double membrane structure characteristic of Gram-negative bacteria. Understanding the ecological role and pathogenic potential of KP95 is crucial, particularly in clinical settings, as it highlights the bacterium's adaptability and the range of infections it can cause in various hosts. This adaptability may contribute to its persistence in diverse environments and underscores its relevance in both human health and veterinary contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain KP95

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain KP95
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain KP95


Gene Summary

Adenine Count

1254642 bp

Thymine Count

1257744 bp

Guanine Count

1661883 bp

Cytosine Count

1649595 bp

Genome Length

5823864 bp

Protein-coding Genes

5423 genes

Non-Coding Genes

394 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
smp-30/gluconolactonase/lre family proteinFG392_02290Not AvailableNegative465307 - 46632337497.3
nucleoid occlusion factor slmaFG392_02295Not AvailableNegative466499 - 46709522825.8
dutp diphosphataseFG392_02300Not AvailableNegative467220 - 46767516032.4
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase coabcFG392_02305Not AvailableNegative467656 - 46887043336.4
jab domain-containing proteinFG392_02310Not AvailablePositive469043 - 46970825014.5
50s ribosomal protein l28FG392_02315Not AvailablePositive469925 - 4701619007.02
50s ribosomal protein l33FG392_02320Not AvailablePositive470182 - 4703496405.98
bifunctional dna-formamidopyrimidine glycosylase/dna-(apurinic or apyrimidinic site) lyaseFG392_02325Not AvailablePositive470485 - 47129430286.8
pantetheine-phosphate adenylyltransferaseFG392_02330Not AvailableNegative471483 - 47196217663.6
glycosyltransferase family 2 proteinFG392_02335Not AvailableNegative471959 - 47273529170.8

Displaying genes 821 – 830 of 5817 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total