Escherichia coli strain MEZEC54 91

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain MEZEC54 91 is a Gram-negative, rod-shaped bacterium that demonstrates mobility through the presence of flagella. As a facultative anaerobe, it can thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, classifying it as mesophilic. This strain is associated with a wide array of hosts, including Homo sapiens, Gallus gallus, Bos taurus, among others, indicating its versatility and adaptability in various biological niches. In terms of pathogenicity, E. coli MEZEC54 91 is known to be a human pathogen, implicated in numerous health conditions. These include urinary tract infections (UTIs), gastrointestinal infections, neonatal meningitis, and more severe complications such as hemolytic uremic syndrome (HUS) and septicemia. The strain's association with both free-living and host-associated environments highlights its ecological role and potential for transmission across different species, including mammals, birds, and even plants. The extensive list of health effects linked to this strain underscores its public health significance, particularly in the context of foodborne infections and urinary tract infections. As E. coli is a common inhabitant of the intestinal tract of humans and animals, understanding the traits of strain MEZEC54 91 can provide insights into the mechanisms underlying its pathogenicity and its interactions with various hosts. This knowledge is crucial for developing strategies to manage infections and mitigate risks associated with this versatile bacterium.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain MEZEC54 91

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain MEZEC54 91
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain MEZEC54 91, whole genome shotgun sequence.

Gene Summary

Adenine Count

1181231 bp

Thymine Count

1183022 bp

Guanine Count

1223756 bp

Cytosine Count

1218265 bp

Genome Length

4806274 bp

Protein-coding Genes

4364 genes

Non-Coding Genes

245 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
flagellar biosynthesis protein flhbFG873_23295Not AvailableNegative4761833 - 476256428473.6
esct/ysct/hrct family type iii secretion system export apparatus proteinFG873_23300Not AvailableNegative4762573 - 476334028201.9
escs/yscs/hrcs family type iii secretion system export apparatus proteinFG873_23305Not AvailableNegative4763342 - 47636029430.85
type 1 fimbriae regulatory protein fimeFG873_23315Not AvailableNegative4764452 - 476504823117.6
type 1 fimbriae regulatory protein fimbFG873_23320Not AvailableNegative4765526 - 476612822994.8
n-acetylneuraminic acid outer membrane channel protein nancFG873_23325Not AvailablePositive4767584 - 476830027889.4
n-acetylneuraminate epimeraseFG873_23330Not AvailablePositive4768320 - 476942639559.3
sialate o-acetylesteraseFG873_23335Not AvailablePositive4769491 - 477047136837.9
hnh endonucleaseFG873_23340Not AvailableNegative4770479 - 47706014623.8
hnh endonucleaseFG873_23345Not AvailablePositive4770683 - 477155533208.6

Displaying genes 4571 – 4580 of 4609 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total