Escherichia coli strain MEZEC47 124

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain MEZEC47 124 is a Gram-negative, rod-shaped bacterium exhibiting facultative anaerobic metabolism. It is characterized by its mobility, facilitated by the presence of flagella, and typically resides in host-associated environments. The strain is mesophilic, with an optimal growth temperature of 37°C, and can exist in pairs or as single cells. This strain demonstrates a diverse range of biotic relationships, being free-living and capable of infecting various hosts, including Homo sapiens, Gallus gallus, Bos taurus, and many others spanning multiple taxa, such as Mammalia and Aves. The extensive host range highlights its ecological versatility and adaptability. E. coli MEZEC47 124 is associated with numerous health effects, particularly in humans, where it can lead to conditions such as urinary tract infections (UTIs), gastrointestinal infections, and neonatal meningitis. The strain is also implicated in severe health complications, including hemolytic uremic syndrome (HUS), septicemia, and colorectal cancer. Such pathogenicity underscores its potential impact on public health and veterinary medicine. Given its ability to cause a wide spectrum of diseases, E. coli strain MEZEC47 124 exemplifies the complex interactions between microbial pathogens and their hosts, emphasizing the importance of monitoring and understanding such strains in both human health and agricultural contexts. The potential for cross-species transmission and the variety of diseases associated with this strain illustrate the significant role that E. coli plays in both ecological and clinical settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain MEZEC47 124

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain MEZEC47 124
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain MEZEC47 124, whole genome shotgun

Gene Summary

Adenine Count

1191776 bp

Thymine Count

1195424 bp

Guanine Count

1241427 bp

Cytosine Count

1230632 bp

Genome Length

4859259 bp

Protein-coding Genes

4386 genes

Non-Coding Genes

275 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
heme exporter protein ccmcFD592_01210Not AvailablePositive262149 - 26288627886.9
heme exporter protein ccmdFD592_01215Not AvailablePositive262883 - 2630927745.59
cytochrome c maturation protein ccmeFD592_01220Not AvailablePositive263089 - 26356817699.4
heme lyase ccmf/nrfe family subunitFD592_01225Not AvailablePositive263565 - 26550871409.6
thiol:disulfide interchange protein dsbeFD592_01230Not AvailablePositive265505 - 26606220810.1
cytochrome c-type biogenesis protein ccmhFD592_01235Not AvailablePositive266059 - 26711139152.4
nitrate/nitrite response regulator protein narpFD592_01240Not AvailableNegative267146 - 26779323636.5
Trna-proNot AvailableNot AvailablePositive270808 - 270884Not Available
cardiolipin transport protein pbgaFD592_01255Not AvailableNegative270959 - 27271967285.8
duf1414 domain-containing proteinFD592_01260Not AvailableNegative272739 - 2729668288.95

Displaying genes 461 – 470 of 4661 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total