Cutibacterium acnes strain P15-014

Cutibacterium acnes strain P15-014 is a Gram-positive, anaerobic bacterium that occupies a host-associated habitat, primarily found in humans (Homo sapiens). This rod-shaped organism lacks mobility and possesses a single membrane, with a single replicon indicating its genomic structure. The strain is classified as mesophilic, with an optimal growth temperature of 37°C. C. acnes is known for its diverse biotic relationships, existing as a free-living organism while also being associated with various health conditions. It is implicated in acute bacterial meningitis, thoracic actinomycosis, and is a well-known contributor to common acne. Additionally, the strain has been linked to more serious health concerns, such as epithelial ovarian cancer and infectious complications that can arise following vertebroplasty or kyphoplasty procedures. The presence of this bacterium in human hosts highlights its dual role as both a part of the normal skin microbiota and an opportunistic pathogen. While it is often benign, under certain conditions, Cutibacterium acnes can lead to significant health issues, suggesting a complex interplay between host factors and microbial behavior. Understanding the environmental and biological contexts in which C. acnes operates may provide further insights into its pathogenic potential and its role in human health.