Cutibacterium acnes strain P15-088

Cutibacterium acnes strain P15-088 is a Gram-positive, non-motile rod-shaped bacterium classified as an anaerobe. This strain is host-associated, primarily inhabiting humans (Homo sapiens) and exhibits a mesophilic temperature range with an optimal growth temperature of 37°C. It possesses one membrane and a single replicon, characteristics typical of many bacteria. C. acnes strain P15-088 is known to have a dual role in human health. While it is commonly associated with the development of acne, it is also implicated in more severe health issues such as acute bacterial meningitis, thoracic actinomycosis, and infectious complications following vertebroplasty or kyphoplasty. Additionally, there are associations with epithelial ovarian cancer, highlighting its potential impact on human health beyond dermatological conditions. This strain’s free-living biotic relationship indicates its capacity to thrive independently within its host environment. The presence of flagella, while noted, does not confer mobility, suggesting that it relies on other mechanisms for colonization and persistence within host tissues. Understanding the ecological role of Cutibacterium acnes strain P15-088 can provide insights into its contributions to both normal skin microbiota and its potential pathogenic effects. This duality emphasizes the complexity of microbial interactions in human health, where a single species can play both beneficial and harmful roles depending on its context within the host.