Cutibacterium acnes strain P15-112

Cutibacterium acnes strain P15-112 is a Gram-positive, anaerobic, rod-shaped bacterium that is associated with human hosts (Homo sapiens). It is a non-motile organism that contains a single membrane and possesses flagella. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic temperature range. This bacterium has been linked to several health effects, including acute bacterial meningitis, thoracic actinomycosis, and various forms of acne, such as common acne. Notably, it has also been implicated in infectious complications following vertebroplasty and kyphoplasty procedures, as well as being associated with epithelial ovarian cancer. These associations highlight its potential impact on human health, particularly in relation to skin and systemic infections. Cutibacterium acnes strain P15-112 is classified as free-living and does not undergo sporulation. The strain is cataloged under accession number VBYR00000000.1, reflecting its unique genetic profile within the wider context of microbial research. From an ecological perspective, the presence of Cutibacterium acnes in human-associated environments suggests its role in the human microbiome, where it may interact with other microbial communities. Its links to various health conditions indicate that while it is a normal inhabitant of human skin, it can also become pathogenic under certain circumstances, illustrating the delicate balance between host-associated bacteria and their potential to cause disease.