Cutibacterium acnes strain P15-181

Cutibacterium acnes strain P15-181 is a Gram-positive bacterium characterized by its rod shape and anaerobic oxygen requirement. This strain is non-motile and possesses flagella. It is classified as mesophilic, with an optimal temperature of 37°C, indicating its adaptation to the human body as a host-associated organism. C. acnes strain P15-181 is notable for its free-living biotic relationship with Homo sapiens. It is commonly recognized for its association with several health issues, including common acne, acute bacterial meningitis, thoracic actinomycosis, and infectious complications following vertebroplasty or kyphoplasty. Additionally, it has been linked to epithelial ovarian cancer. The strain has a single replicon and one membrane, aligning with characteristics typical of many anaerobic bacteria. It does not form spores, which is consistent with its ecological niche and lifestyle. The presence of C. acnes in the human microbiome plays a dual role; while it can contribute to acne and other conditions, it also serves as a normal skin commensal. This underscores the complexity of its interactions within human health, highlighting the importance of understanding microbial dynamics in relation to disease and the host environment.