Cutibacterium acnes strain T28794

Cutibacterium acnes strain T28794 is a Gram-positive, rod-shaped anaerobic bacterium predominantly associated with its host, Homo sapiens. This bacterium exhibits a unique ecological niche, thriving within the human body, where it can be found in various environments. C. acnes is characterized by the absence of mobility, as it does not possess flagella. It has a single membrane and a single replicon, which is indicative of its simple genomic structure. The optimal growth temperature for C. acnes T28794 is 37°C, placing it within the mesophilic temperature range, which aligns with the typical conditions found in the human body. This strain has been implicated in several health conditions, including acute bacterial meningitis, thoracic actinomycosis, and common acne. Notably, it has also been associated with more severe health implications such as infectious complications following vertebroplasty and kyphoplasty, as well as a potential link to epithelial ovarian cancer. In terms of its biotic relationships, C. acnes is considered free-living, yet it thrives in a host-associated environment. Its nonsporulating nature suggests that it relies on stable conditions within the host for survival and proliferation. Understanding the ecological role and pathogenic potential of Cutibacterium acnes strain T28794 is crucial, particularly in the context of its associations with various diseases. Its predominant presence in the human microbiome highlights the complex interplay between host and microbial communities, influencing both health and disease outcomes.