Cutibacterium acnes strain T28840

Cutibacterium acnes strain T28840 is a Gram-positive, rod-shaped bacterium that is classified as an anaerobe, indicating that it thrives in environments devoid of oxygen. This strain is adapted to a mesophilic temperature range, with an optimal growth temperature of 37°C, making it well-suited for colonization in human hosts, specifically Homo sapiens. As a free-living organism, Cutibacterium acnes strain T28840 is not motile and does not possess flagella, which limits its movement. It has a single membrane and a single replicon, characteristics typical of many bacterial species. This strain is nonsporulating, which means that it does not produce spores as a means of surviving adverse conditions. Cutibacterium acnes is known for its association with various health conditions, including common acne, acute bacterial meningitis, thoracic actinomycosis, and infectious complications following vertebroplasty or kyphoplasty. Notably, it has also been implicated in epithelial ovarian cancer. The presence of Cutibacterium acnes in the human microbiome highlights its dual role as both a commensal organism and a potential pathogen. While it is often part of the normal skin flora, its overgrowth can lead to skin conditions such as acne. This underscores the importance of maintaining a balanced microbiome, as disruptions can have significant health implications, demonstrating the complex interplay between microbial communities and human health.