Cutibacterium acnes strain T29015

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Propionibacteriales

Family

Propionibacteriaceae

Genus

Cutibacterium

Description

Cutibacterium acnes strain T29015 is a Gram-positive, anaerobic bacterium that predominantly resides in host-associated environments, specifically in humans (Homo sapiens). This organism is characterized by its rod shape and lack of mobility, which is consistent with its free-living biotic relationship. It possesses a single membrane and is nonsporulating, indicating a reliance on its host for survival. The optimal temperature for C. acnes strain T29015 is 37°C, aligning with its mesophilic nature, which is typical for many human-associated microorganisms. This strain is notable for its involvement in various health conditions, including acute bacterial meningitis, thoracic actinomycosis, and common acne. Additionally, it has been implicated in more severe health issues such as infectious complications following vertebroplasty/kyphoplasty and even epithelial ovarian cancer. Given its association with both benign and serious health outcomes, C. acnes strain T29015 exemplifies the dual nature of human-associated microbiota, where certain strains can contribute to health while others may be linked to disease. Its presence in the human body underscores the complexity of the microbiome and highlights the need for further research to understand its roles in both health and disease contexts. The strain is cataloged under the accession number VBXY00000000.1, facilitating its identification and study in microbial research.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderPropionibacteriales
FamilyPropionibacteriaceae
GenusCutibacterium
SpeciesCutibacterium acnes
Strainstrain T29015

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Cutibacterium acnes strain T29015
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Cutibacterium acnes strain T29015

Gene Summary

Adenine Count

510474 bp

Thymine Count

477657 bp

Guanine Count

718572 bp

Cytosine Count

771796 bp

Genome Length

2478499 bp

Protein-coding Genes

2385 genes

Non-Coding Genes

52 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinFD525_02245Not AvailableNegative445406 - 4456248211.31
flavin reductase family proteinFD525_02255Not AvailablePositive446098 - 44665820129.2
hypothetical proteinFD525_02260Not AvailablePositive446704 - 4469287876.43
abc-f family atp-binding cassette domain-containing proteinFD525_02265Not AvailablePositive447133 - 44766618583.4
hypothetical proteinFD525_02270Not AvailablePositive447617 - 44799413777.3
abc transporter atp-binding proteinFD525_02275Not AvailablePositive447991 - 44838613747.9
adenosylcobyric acid synthaseFD525_02280Not AvailableNegative448302 - 44862211424.6
hypothetical proteinFD525_02285Not AvailableNegative448864 - 4491008323.9
hypothetical proteinFD525_02290Not AvailableNegative449215 - 44956211917.9
hypothetical proteinFD525_02295Not AvailableNegative449532 - 44984010965.0

Displaying genes 441 – 450 of 2437 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Acute bacterial meningitisCausesPMC6306750
Thoracic actinomycosisCausesPMC6956836
AcneCausesPMC7808774
Epithelial ovarian cancerCausesPMC10587687
AcneCausesPMC13314309
Infectious complications after vertebroplasty/kyphoplastyCausesPMC7379344
Common acneCausesPMC3388012
AcneCausesPMC8549750

Displaying health effects 1 – 8 of 8 in total