Cutibacterium acnes strain T29350

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Propionibacteriales

Family

Propionibacteriaceae

Genus

Cutibacterium

Description

Cutibacterium acnes strain T29350 is a Gram-positive, anaerobic bacterium primarily associated with human hosts (Homo sapiens). This species exhibits a rod shape and is non-motile, lacking flagella despite their presence in some bacterial species. It thrives at an optimal temperature of 37°C, fitting within the mesophilic temperature range. C. acnes strain T29350 is known for its role in various health conditions. It is implicated in acute bacterial meningitis, thoracic actinomycosis, and is most commonly associated with acne and infectious complications following vertebroplasty or kyphoplasty. Additionally, some studies suggest a potential link to epithelial ovarian cancer. The bacterium is nonsporulating and has one replicon and a single membrane. Its biotic relationship is categorized as free-living, emphasizing its capability to exist independently in its host-associated habitat. The presence of C. acnes in human skin suggests a complex ecological role, where it may contribute to skin health while also being associated with pathological conditions. Understanding its dual role is crucial for developing therapeutic strategies, especially considering its involvement in acne and other health issues. This highlights the importance of further research into the specific mechanisms by which C. acnes influences human health and disease.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderPropionibacteriales
FamilyPropionibacteriaceae
GenusCutibacterium
SpeciesCutibacterium acnes
Strainstrain T29350

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Cutibacterium acnes strain T29350
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Cutibacterium acnes strain T29350

Gene Summary

Adenine Count

510879 bp

Thymine Count

479293 bp

Guanine Count

722453 bp

Cytosine Count

766624 bp

Genome Length

2479249 bp

Protein-coding Genes

2263 genes

Non-Coding Genes

51 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
elongation factor pFD527_01240Not AvailableNegative229079 - 22964821121.0
polyphosphate kinase 2FD527_01245Not AvailablePositive229994 - 23087534410.7
hypothetical proteinFD527_01250Not AvailableNegative230872 - 2310907145.56
capa family proteinFD527_01255Not AvailablePositive231098 - 23211736004.5
3-dehydroquinate synthaseFD527_01260Not AvailableNegative232260 - 23334538820.1
shikimate kinaseFD527_01265Not AvailableNegative233342 - 23385118099.7
chorismate synthaseFD527_01270Not AvailableNegative233848 - 23504441841.3
shikimate dehydrogenaseFD527_01275Not AvailableNegative235058 - 23586428279.1
endolytic transglycosylase mltgFD527_01280Not AvailableNegative235896 - 23700540740.5
holliday junction resolvase ruvxFD527_01285Not AvailableNegative237002 - 23748417272.6

Displaying genes 231 – 240 of 2314 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Acute bacterial meningitisCausesPMC6306750
Thoracic actinomycosisCausesPMC6956836
AcneCausesPMC7808774
Epithelial ovarian cancerCausesPMC10587687
AcneCausesPMC13314309
Infectious complications after vertebroplasty/kyphoplastyCausesPMC7379344
Common acneCausesPMC3388012
AcneCausesPMC8549750

Displaying health effects 1 – 8 of 8 in total