Cutibacterium acnes strain T29350

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Propionibacteriales

Family

Propionibacteriaceae

Genus

Cutibacterium

Description

Cutibacterium acnes strain T29350 is a Gram-positive, anaerobic bacterium primarily associated with human hosts (Homo sapiens). This species exhibits a rod shape and is non-motile, lacking flagella despite their presence in some bacterial species. It thrives at an optimal temperature of 37°C, fitting within the mesophilic temperature range. C. acnes strain T29350 is known for its role in various health conditions. It is implicated in acute bacterial meningitis, thoracic actinomycosis, and is most commonly associated with acne and infectious complications following vertebroplasty or kyphoplasty. Additionally, some studies suggest a potential link to epithelial ovarian cancer. The bacterium is nonsporulating and has one replicon and a single membrane. Its biotic relationship is categorized as free-living, emphasizing its capability to exist independently in its host-associated habitat. The presence of C. acnes in human skin suggests a complex ecological role, where it may contribute to skin health while also being associated with pathological conditions. Understanding its dual role is crucial for developing therapeutic strategies, especially considering its involvement in acne and other health issues. This highlights the importance of further research into the specific mechanisms by which C. acnes influences human health and disease.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderPropionibacteriales
FamilyPropionibacteriaceae
GenusCutibacterium
SpeciesCutibacterium acnes
Strainstrain T29350

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Cutibacterium acnes strain T29350
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Cutibacterium acnes strain T29350

Gene Summary

Adenine Count

510879 bp

Thymine Count

479293 bp

Guanine Count

722453 bp

Cytosine Count

766624 bp

Genome Length

2479249 bp

Protein-coding Genes

2263 genes

Non-Coding Genes

51 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc transporter substrate-binding proteinFD527_00760Not AvailablePositive138919 - 14040653496.6
abc transporter permeaseFD527_00765Not AvailablePositive140403 - 14138034799.5
abc transporter permeaseFD527_00770Not AvailablePositive141377 - 14218928140.8
abc transporter atp-binding proteinFD527_00775Not AvailablePositive142189 - 14299828953.2
abc transporter atp-binding proteinFD527_00780Not AvailablePositive142998 - 14378328613.6
phosphoglycerate dehydrogenaseFD527_00785Not AvailablePositive143830 - 14502042835.5
histidinol phosphataseFD527_00790Not AvailableNegative145064 - 14585228377.2
ribosome small subunit-dependent gtpase aFD527_00800Not AvailableNegative146905 - 14790635543.3
3-phosphoshikimate 1-carboxyvinyltransferaseFD527_00805Not AvailableNegative147908 - 14919745301.8
doxx family membrane proteinFD527_00810Not AvailableNegative149187 - 14981922025.0

Displaying genes 141 – 150 of 2314 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Acute bacterial meningitisCausesPMC6306750
Thoracic actinomycosisCausesPMC6956836
AcneCausesPMC7808774
Epithelial ovarian cancerCausesPMC10587687
AcneCausesPMC13314309
Infectious complications after vertebroplasty/kyphoplastyCausesPMC7379344
Common acneCausesPMC3388012
AcneCausesPMC8549750

Displaying health effects 1 – 8 of 8 in total