Cutibacterium acnes strain T29350

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Propionibacteriales

Family

Propionibacteriaceae

Genus

Cutibacterium

Description

Cutibacterium acnes strain T29350 is a Gram-positive, anaerobic bacterium primarily associated with human hosts (Homo sapiens). This species exhibits a rod shape and is non-motile, lacking flagella despite their presence in some bacterial species. It thrives at an optimal temperature of 37°C, fitting within the mesophilic temperature range. C. acnes strain T29350 is known for its role in various health conditions. It is implicated in acute bacterial meningitis, thoracic actinomycosis, and is most commonly associated with acne and infectious complications following vertebroplasty or kyphoplasty. Additionally, some studies suggest a potential link to epithelial ovarian cancer. The bacterium is nonsporulating and has one replicon and a single membrane. Its biotic relationship is categorized as free-living, emphasizing its capability to exist independently in its host-associated habitat. The presence of C. acnes in human skin suggests a complex ecological role, where it may contribute to skin health while also being associated with pathological conditions. Understanding its dual role is crucial for developing therapeutic strategies, especially considering its involvement in acne and other health issues. This highlights the importance of further research into the specific mechanisms by which C. acnes influences human health and disease.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderPropionibacteriales
FamilyPropionibacteriaceae
GenusCutibacterium
SpeciesCutibacterium acnes
Strainstrain T29350

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Cutibacterium acnes strain T29350
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Cutibacterium acnes strain T29350

Gene Summary

Adenine Count

510879 bp

Thymine Count

479293 bp

Guanine Count

722453 bp

Cytosine Count

766624 bp

Genome Length

2479249 bp

Protein-coding Genes

2263 genes

Non-Coding Genes

51 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
1-phosphofructokinase family hexose kinaseFD527_05850Not AvailablePositive1155119 - 115606932560.8
pts lactose transporter subunit iicFD527_05855Not AvailablePositive1156079 - 115809168221.2
hpr family phosphocarrier proteinFD527_05860Not AvailablePositive1158127 - 11583848405.91
sdr family oxidoreductaseFD527_05865Not AvailableNegative1158448 - 115924828614.9
nad(p)/fad-dependent oxidoreductaseFD527_05870Not AvailableNegative1159264 - 116042440903.4
mfs transporterFD527_05875Not AvailableNegative1160692 - 116226956956.3
o-antigen ligase family proteinFD527_05880Not AvailableNegative1162474 - 116385649599.5
gfo/idh/moca family oxidoreductaseFD527_05885Not AvailableNegative1163958 - 116495035566.5
degt/dnrj/eryc1/strs family aminotransferaseFD527_05890Not AvailableNegative1164950 - 116606239273.6
n-acetyltransferaseFD527_05895Not AvailableNegative1166146 - 116676321704.5

Displaying genes 1101 – 1110 of 2314 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Acute bacterial meningitisCausesPMC6306750
Thoracic actinomycosisCausesPMC6956836
AcneCausesPMC7808774
Epithelial ovarian cancerCausesPMC10587687
AcneCausesPMC13314309
Infectious complications after vertebroplasty/kyphoplastyCausesPMC7379344
Common acneCausesPMC3388012
AcneCausesPMC8549750

Displaying health effects 1 – 8 of 8 in total