Cutibacterium acnes strain W65215

Cutibacterium acnes strain W65215 is a Gram-positive, anaerobic bacterium that primarily resides in association with its host, Homo sapiens. This rod-shaped organism is characterized by its non-motility and the presence of flagella. It is mesophilic, with an optimal growth temperature of 37°C, indicating a preference for the human body temperature range. As a free-living bacterium, C. acnes strain W65215 is notable for its involvement in several health conditions, including common acne, acute bacterial meningitis, thoracic actinomycosis, and even infectious complications following vertebroplasty or kyphoplasty. Additionally, it has been associated with epithelial ovarian cancer, highlighting its potential role in more complex pathological processes. The strain contains a single replicon and one membrane, indicative of its relatively simple cellular structure. Importantly, C. acnes does not undergo sporulation, which is consistent with its lifestyle and ecological niche within the human host. The presence of this organism in various human health issues underscores its dual role as both a commensal and a potential pathogen, reflecting the complex interactions that can occur between host-associated microorganisms and their human hosts. Understanding the role of C. acnes in health and disease can provide insights into microbial ecology and the implications for human health management.