Klebsiella pneumoniae strain EuSCAPE_GR006

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_GR006 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism as a chemoheterotroph. It typically exists in host-associated habitats and can be found in various organisms, including humans (Homo sapiens) and several other species across the animal kingdom and plants. This strain features a single replicon and possesses two membranes, indicating its classification within the Proteobacteria phylum. EuSCAPE_GR006 can be observed in various arrangements, including chains, pairs, and singles, and it is motile, equipped with flagella, which enhances its ability to adapt to different environments. The optimal growth temperature for this strain is 37°C, and it thrives within a mesophilic temperature range. This bacterium is associated with numerous health effects in humans, including severe conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its pathogenicity is notable, as it can cause infections in diverse tissues and systems, leading to significant clinical implications. Ecologically, Klebsiella pneumoniae strain EuSCAPE_GR006 underscores the complex interactions within host-associated environments, where it can act as both a free-living organism and a potential pathogen. This dual role highlights the importance of understanding microbial dynamics, particularly in relation to human health and disease, as well as the potential for environmental reservoirs of pathogenic strains.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_GR006

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_GR006
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_GR006 genome assembly,

Gene Summary

Adenine Count

1251912 bp

Thymine Count

1249126 bp

Guanine Count

1642678 bp

Cytosine Count

1648597 bp

Genome Length

5792313 bp

Protein-coding Genes

5204 genes

Non-Coding Genes

306 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
gntr family transcriptional regulatorSAMEA3649597_01656Not AvailableNegative1747426 - 174877850249.7
carboxymuconolactone decarboxylase family proteinSAMEA3649597_01657Not AvailablePositive1748867 - 174929815847.0
glutaredoxin-like protein nrdhSAMEA3649597_01658Not AvailablePositive1749482 - 17497279254.15
ribonucleotide reduction protein nrdiSAMEA3649597_01659Not AvailablePositive1749724 - 175013415322.4
ribonucleotide reductase of class ib (aerobic) subunit alphaSAMEA3649597_01660Not AvailablePositive1750107 - 175224880092.2
ribonucleotide-diphosphate reductase subunit betaSAMEA3649597_01661Not AvailablePositive1752259 - 175322136141.6
l-proline glycine betaine abc transport system permease provSAMEA3649597_01662Not AvailablePositive1753578 - 175478044094.7
l-proline glycine betaine abc transport system permease protein prowSAMEA3649597_01663Not AvailablePositive1754773 - 175584037643.3
l-proline glycine betaine binding abc transporter protein proxSAMEA3649597_01664Not AvailablePositive1755904 - 175690236174.7
azlc family proteinSAMEA3649597_01665Not AvailablePositive1757081 - 175782726376.6

Displaying genes 1801 – 1810 of 5510 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total