Klebsiella pneumoniae strain EuSCAPE_ES263

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES263 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe. It exhibits a variety of cell arrangements, including chains, pairs, and singles. This strain is a chemoheterotroph, deriving its energy from organic compounds, and it possesses flagella, indicating mobility. It thrives optimally at 37°C, within a mesophilic temperature range. EuSCAPE_ES263 is associated with various hosts, notably Homo sapiens, but also includes species from Gallus gallus, Metazoa, Viridiplantae, Danio rerio, Ovis aries, Phasianidae, Sus scrofa, Aves, Canis lupus familiaris, Amphibia, and Equidae. This wide host range highlights its adaptability and potential for cross-species infections. The strain is known to cause a range of serious health effects in humans, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. It is also implicated in conditions such as septicemia, neonatal sepsis, and pulmonary infections, showcasing its pathogenic potential. Notably, Klebsiella pneumoniae is nonsporulating, which may influence its survival and persistence in different environments. As a free-living organism, Klebsiella pneumoniae strain EuSCAPE_ES263 underscores the importance of understanding microbial interactions within various ecological niches. Its pathogenicity in humans and diverse host range suggest a significant role in both environmental and clinical settings, emphasizing the need for ongoing surveillance and research into its behaviors and impacts on health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES263

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES263
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES263 genome assembly,

Gene Summary

Adenine Count

1179715 bp

Thymine Count

1179826 bp

Guanine Count

1569315 bp

Cytosine Count

1594480 bp

Genome Length

5523336 bp

Protein-coding Genes

5029 genes

Non-Coding Genes

150 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
paraquat-inducible protein bSAMEA3649586_00183Not AvailableNegative204794 - 20742794779.8
membrane proteinSAMEA3649586_00184Not AvailableNegative207396 - 20867947863.0
free methionine-r-sulfoxide reductaseSAMEA3649586_00185Not AvailablePositive208755 - 20930920135.2
proq: influences osmotic activation of compatible solute propSAMEA3649586_00186Not AvailablePositive209407 - 21008424976.0
carboxy-terminal proteaseSAMEA3649586_00187Not AvailablePositive210104 - 21215276675.3
heat shock protein htpxSAMEA3649586_00188Not AvailablePositive212388 - 21327232048.5
transport proteinSAMEA3649586_00189Not AvailableNegative213338 - 21470847803.2
transcriptional regulator kdgrSAMEA3649586_00190Not AvailablePositive214886 - 21567729980.0
putative outer membrane or exportedSAMEA3649586_00191Not AvailableNegative215734 - 2159738403.45
uncharacterised proteinSAMEA3649586_00192Not AvailablePositive216351 - 21664110611.9

Displaying genes 261 – 270 of 5179 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total