Klebsiella pneumoniae strain EuSCAPE_ES262

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES262 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. It is characterized by its ability to form chains, pairs, and single cells, and possesses flagella, indicating mobility. This strain is mesophilic, with an optimal growth temperature of 37°C. EuSCAPE_ES262 is primarily associated with various hosts, including Homo sapiens and several animal species such as Gallus gallus, Sus scrofa, and Canis lupus familiaris, among others. Its free-living nature allows it to thrive in diverse environments, though it is often found in association with living organisms. The pathogenicity of Klebsiella pneumoniae strain EuSCAPE_ES262 is significant, as it is linked to a wide range of health effects, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The bacterium is notorious for causing severe conditions such as septicemia, neonatal sepsis, and pyogenic liver abscesses. These health impacts underscore its role as a notable human pathogen. The presence of this strain in multiple hosts highlights its ecological versatility and adaptability. This adaptability may contribute to its persistence in various environments and its capacity to cause infections across different host species. Understanding the ecological relationships and pathogenic mechanisms of Klebsiella pneumoniae is essential for developing effective treatment and prevention strategies against the infections it causes.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES262

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES262
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES262 genome assembly,

Gene Summary

Adenine Count

1200389 bp

Thymine Count

1199360 bp

Guanine Count

1583026 bp

Cytosine Count

1594712 bp

Genome Length

5577487 bp

Protein-coding Genes

5010 genes

Non-Coding Genes

282 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Putative tail terminator proteinSAMEA3649584_02152Not AvailableNegative2362437 - 236282913988.7
Hypothetical proteinSAMEA3649584_02153Not AvailableNegative2362826 - 236337720184.9
Hypothetical proteinSAMEA3649584_02154Not AvailableNegative2363379 - 236376213710.1
uncharacterised proteinSAMEA3649584_02155Not AvailableNegative2363749 - 23639828507.3
Hypothetical proteinSAMEA3649584_02156Not AvailableNegative2363992 - 23642469459.31
Putative head-tail joining proteinSAMEA3649584_02157Not AvailableNegative2364248 - 236464314377.0
Major capsid proteinSAMEA3649584_02158Not AvailableNegative2364965 - 236591834215.2
Hypothetical proteinSAMEA3649584_02159Not AvailableNegative2365929 - 236671427877.8
Head morphogenesis proteinSAMEA3649584_02160Not AvailableNegative2366799 - 236791141230.8
Putative portal vertex proteinSAMEA3649584_02161Not AvailableNegative2367895 - 236929551767.6

Displaying genes 11 – 20 of 5292 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total