Klebsiella pneumoniae strain EuSCAPE_ES283

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES283 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in various oxygen conditions. It is categorized as a chemoheterotroph, utilizing organic compounds for energy. This strain is capable of mobility due to the presence of flagella and typically exists in chains, pairs, or as single cells. The optimal growth temperature for Klebsiella pneumoniae EuSCAPE_ES283 is 37°C, placing it within the mesophilic temperature range. This strain is notable for its association with a variety of hosts, including Homo sapiens, as well as various animals such as Gallus gallus, Danio rerio, and Sus scrofa, among others. This diverse host range suggests that it is adaptable and can survive in different biological environments. Klebsiella pneumoniae is known to be pathogenic to humans, causing a range of health issues including bacteremia, urinary tract infections, pneumonia, and sepsis. It is implicated in serious conditions such as pyogenic liver abscesses and neonatal sepsis. The bacterium does not form spores, which may influence its survival strategies in host environments. In terms of its ecological role, Klebsiella pneumoniae strain EuSCAPE_ES283 can be classified as free-living, indicating its ability to exist independently in various habitats while also having the potential to cause disease in multiple host species. This duality highlights the importance of understanding its behavior in both environmental and clinical contexts, particularly in relation to its pathogenicity and transmission dynamics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES283

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES283
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES283 genome assembly,

Gene Summary

Adenine Count

1238821 bp

Thymine Count

1239952 bp

Guanine Count

1656999 bp

Cytosine Count

1612500 bp

Genome Length

5748272 bp

Protein-coding Genes

5127 genes

Non-Coding Genes

357 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
acetyltransferase, (gnat) familySAMEA3649626_00406Not AvailablePositive407975 - 40845417986.5
laci family transcriptional repressorSAMEA3649626_00407Not AvailableNegative408415 - 40943136810.1
2-acylglycerophosphoethanolamine acyltransferaseSAMEA3649626_00408Not AvailablePositive410053 - 41221280264.6
lysophospholipid transporter lpltSAMEA3649626_00409Not AvailablePositive412205 - 41339841686.3
oxidoreductaseSAMEA3649626_00410Not AvailableNegative413501 - 41454138498.8
lipoprotein ygdrSAMEA3649626_00411Not AvailableNegative414762 - 4149807913.47
integral membrane protein tercSAMEA3649626_00412Not AvailableNegative415104 - 41581726229.2
dna mismatch repair endonuclease muthSAMEA3649626_00413Not AvailableNegative415881 - 41657625467.9
adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolaseSAMEA3649626_00414Not AvailablePositive417259 - 41778920736.9
phosphocarrier protein kinase/phosphorylaseSAMEA3649626_00415Not AvailablePositive417802 - 42004883510.3

Displaying genes 731 – 740 of 5484 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total