Klebsiella pneumoniae strain EuSCAPE_ES277

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES277 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle, allowing it to thrive in various oxygen conditions. This strain is classified as a chemoheterotroph, deriving energy from organic compounds. It typically exists in chains, pairs, or as single cells, and possesses flagella, indicating its mobility. This bacterium is mesophilic, with an optimal growth temperature of 37°C, which is coincidentally the average human body temperature, suggesting an adaptation to a host-associated habitat. K. pneumoniae strain EuSCAPE_ES277 is free-living but has a wide range of hosts, including various species within Homo sapiens, Gallus gallus, Metazoa, Viridiplantae, Danio rerio, Ovis aries, Phasianidae, Sus scrofa, Aves, Canis lupus familiaris, Amphibia, and Equidae. K. pneumoniae is known for its significant pathogenicity in humans, contributing to a variety of serious health issues such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain's ability to cause multiple infections underscores its role as a critical opportunistic pathogen in clinical settings. In summary, K. pneumoniae strain EuSCAPE_ES277 exemplifies the adaptability and pathogenic potential of bacteria associated with a wide range of hosts. Its presence in diverse environments and association with numerous health complications highlights the need for continued surveillance and research regarding its impact on human health and its ecological relationships.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES277

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES277
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES277 genome assembly,

Gene Summary

Adenine Count

1250178 bp

Thymine Count

1253027 bp

Guanine Count

1646167 bp

Cytosine Count

1633219 bp

Genome Length

5782591 bp

Protein-coding Genes

5330 genes

Non-Coding Genes

179 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinSAMEA3649615_02263Not AvailableNegative2405224 - 240556211982.3
Hypothetical proteinSAMEA3649615_02264Not AvailablePositive2406947 - 24071929005.53
Hnh endonucleaseSAMEA3649615_02265Not AvailablePositive2407248 - 240758913157.9
Terminase small subunitSAMEA3649615_02266Not AvailablePositive2407772 - 240823616947.5
Terminase large subunit-like proteinSAMEA3649615_02267Not AvailablePositive2408190 - 240993264954.8
Portal proteinSAMEA3649615_02268Not AvailablePositive2409932 - 241123948647.1
Head maturation proteaseSAMEA3649615_02269Not AvailablePositive2411252 - 241210029628.1
Major head subunitSAMEA3649615_02270Not AvailablePositive2412110 - 241332743639.0
Head-tail connector iSAMEA3649615_02271Not AvailablePositive2413370 - 241363910096.8
Head-tail connector iiSAMEA3649615_02272Not AvailablePositive2413639 - 241396512307.6

Displaying genes 81 – 90 of 5509 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total