Klebsiella pneumoniae strain EuSCAPE_ES253

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES253 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism and is categorized as a chemoheterotroph, obtaining energy from organic compounds. This strain is notable for its ability to exist in various arrangements, including chains, pairs, and singles, and it possesses flagella, which contribute to its mobility. EuSCAPE_ES253 is mesophilic, thriving optimally at a temperature of 37°C, and has a single replicon and a double membrane structure. This bacterium is primarily associated with hosts, including humans (Homo sapiens), various animal species, and plants, indicating a broad ecological niche. It is involved in multiple biotic relationships, being free-living and capable of infecting a range of hosts, including mammals like dogs (Canis lupus familiaris) and livestock such as pigs (Sus scrofa) and sheep (Ovis aries). Klebsiella pneumoniae EuSCAPE_ES253 is clinically significant due to its pathogenicity in humans, causing a variety of serious health conditions, including bacteremia, urinary tract infections, pneumonia, and sepsis. Its ability to infect diverse hosts suggests a versatile adaptation mechanism. The strain's association with such a wide array of infections highlights its potential impact on public health and the importance of monitoring its spread and antimicrobial resistance. Understanding its ecological relationships may further inform strategies for managing infections in both human and veterinary medicine.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES253

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES253
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES253 genome assembly,

Gene Summary

Adenine Count

1181941 bp

Thymine Count

1176802 bp

Guanine Count

1558984 bp

Cytosine Count

1605495 bp

Genome Length

5523222 bp

Protein-coding Genes

5065 genes

Non-Coding Genes

148 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
integrase catalytic subunitSAMEA3649569_05185Not AvailableNegative5491875 - 549272332471.6
transposaseSAMEA3649569_05186Not AvailableNegative5492720 - 549303111149.4
tunicamycin resistance proteinSAMEA3649569_05187Not AvailableNegative5493123 - 549366520630.9
aminoglycoside acetyltransferaseSAMEA3649569_05188Not AvailableNegative5493678 - 549453830610.5
transposase for is26SAMEA3649569_05189Not AvailablePositive5494645 - 549491111030.3
beta-lactamase oxa-10 precursorSAMEA3649569_05191Not AvailablePositive5498263 - 549906030360.4
transcriptional regulatorSAMEA3649569_05192Not AvailableNegative5499362 - 550027333408.4
uncharacterised proteinSAMEA3649569_05193Not AvailablePositive5500816 - 550144824812.4
transposaseSAMEA3649569_05194Not AvailableNegative5501477 - 550288053455.1
mannose-1-phosphate guanylyltransferaseSAMEA3649569_05195Not AvailableNegative5503675 - 550503951085.6

Displaying genes 5191 – 5200 of 5213 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total