Klebsiella pneumoniae strain EuSCAPE_ES248

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES248 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and a chemoheterotroph. It typically forms chains, pairs, or exists as single cells. This strain possesses flagella, which contributes to its mobility. It is mesophilic, with an optimal growth temperature of 37°C, making it well-suited to the human body and other warm-blooded organisms. EuSCAPE_ES248 has a complex biotic relationship, being free-living but also associated with various hosts, including Homo sapiens, Gallus gallus, several metazoans, and other vertebrates like Danio rerio and Sus scrofa. This wide host range indicates its adaptability and potential for transmission across different species. The strain is associated with a myriad of health effects, notably including bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections. Its pathogenicity is particularly pronounced in humans, where it can lead to severe conditions such as sepsis and neonatal infections. The presence of this bacterium in clinical settings highlights its role as a significant opportunistic pathogen. Given its diverse habitats and ability to cause a range of infections, Klebsiella pneumoniae strain EuSCAPE_ES248 plays an important ecological role in human health and disease dynamics. Its adaptability to various environments and hosts underscores the importance of monitoring this strain in clinical and environmental contexts to manage its pathogenic potential effectively.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES248

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES248
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES248


Gene Summary

Adenine Count

1225822 bp

Thymine Count

1222146 bp

Guanine Count

1630996 bp

Cytosine Count

1608262 bp

Genome Length

5687226 bp

Protein-coding Genes

5186 genes

Non-Coding Genes

191 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dehydrogenaseSAMEA3649564_00714Not AvailableNegative741253 - 74223033833.0
lysr family transcriptional regulatorSAMEA3649564_00715Not AvailablePositive742399 - 74329533557.6
putative cell envelope integrity inner membrane protein tolaSAMEA3649564_00716Not AvailablePositive743360 - 74389318955.3
fmn oxidoreductaseSAMEA3649564_00717Not AvailableNegative744127 - 74522739582.0
acyl-coa dehydrogenaseSAMEA3649564_00718Not AvailableNegative745335 - 74694260345.1
metabolite transport proteinSAMEA3649564_00719Not AvailablePositive747218 - 74845044575.3
drug/metabolite transporter permeaseSAMEA3649564_00720Not AvailableNegative748491 - 74940533566.1
spermidine/putrescine abc transporterSAMEA3649564_00721Not AvailablePositive749607 - 75070740862.6
tetr family transcriptional regulatorSAMEA3649564_00722Not AvailableNegative750683 - 75126121885.4
putative acetyltransferaseSAMEA3649564_00723Not AvailablePositive751900 - 75243620706.5

Displaying genes 851 – 860 of 5377 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total