Klebsiella pneumoniae strain EuSCAPE_ES241

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES241 is a Gram-negative, rod-shaped bacterium that demonstrates a facultative anaerobic metabolism as a chemoheterotroph. This strain is characterized by its ability to exist in various cell arrangements, including chains, pairs, and singles, and possesses flagella, allowing for mobility. Optimal growth occurs at 37°C, placing it within the mesophilic temperature range. This bacterium is primarily associated with hosts, including Homo sapiens, various animal species (e.g., Gallus gallus, Sus scrofa, Canis lupus familiaris), and even some plants (Viridiplantae). Klebsiella pneumoniae EuSCAPE_ES241 has been implicated in numerous health complications, particularly in humans, where it can cause a range of serious infections such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain's pathogenicity is evident in its ability to affect multiple organ systems and can lead to severe conditions like pyogenic liver abscesses and neonatal sepsis. This bacterium maintains a biotic relationship as a free-living organism and is non-sporulating. It has a single replicon and is surrounded by two membranes, which is characteristic of its Gram-negative classification. Given its diverse host range and significant pathogenic potential, Klebsiella pneumoniae EuSCAPE_ES241 highlights the importance of monitoring and understanding antibiotic resistance and the ecological dynamics of pathogens within both human and animal populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES241

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES241
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES241 genome assembly,

Gene Summary

Adenine Count

1178686 bp

Thymine Count

1175379 bp

Guanine Count

1569060 bp

Cytosine Count

1589634 bp

Genome Length

5512759 bp

Protein-coding Genes

4900 genes

Non-Coding Genes

358 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3649557_01784Not AvailableNegative1870200 - 18703887284.7
Replication endonucleaseSAMEA3649557_01785Not AvailableNegative1870575 - 187298092090.0
Dna adenine methylaseSAMEA3649557_01786Not AvailableNegative1872961 - 187384833513.5
Trar/dksa family transcriptional regulatorSAMEA3649557_01787Not AvailableNegative1873845 - 18740728268.95
Hypothetical proteinSAMEA3649557_01788Not AvailableNegative1874072 - 18743058635.23
Hypothetical proteinSAMEA3649557_01789Not AvailableNegative1874373 - 187471412947.7
Hypothetical proteinSAMEA3649557_01790Not AvailableNegative1874678 - 18748787543.38
Regulatory protein ciiSAMEA3649557_01791Not AvailableNegative1874886 - 187539518347.2
Regulatory proteinSAMEA3649557_01792Not AvailableNegative1875430 - 18756668927.07
Repressor ciSAMEA3649557_01793Not AvailablePositive1875767 - 187638723076.5

Displaying genes 41 – 50 of 5258 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total