Klebsiella pneumoniae strain EuSCAPE_ES241

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES241 is a Gram-negative, rod-shaped bacterium that demonstrates a facultative anaerobic metabolism as a chemoheterotroph. This strain is characterized by its ability to exist in various cell arrangements, including chains, pairs, and singles, and possesses flagella, allowing for mobility. Optimal growth occurs at 37°C, placing it within the mesophilic temperature range. This bacterium is primarily associated with hosts, including Homo sapiens, various animal species (e.g., Gallus gallus, Sus scrofa, Canis lupus familiaris), and even some plants (Viridiplantae). Klebsiella pneumoniae EuSCAPE_ES241 has been implicated in numerous health complications, particularly in humans, where it can cause a range of serious infections such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain's pathogenicity is evident in its ability to affect multiple organ systems and can lead to severe conditions like pyogenic liver abscesses and neonatal sepsis. This bacterium maintains a biotic relationship as a free-living organism and is non-sporulating. It has a single replicon and is surrounded by two membranes, which is characteristic of its Gram-negative classification. Given its diverse host range and significant pathogenic potential, Klebsiella pneumoniae EuSCAPE_ES241 highlights the importance of monitoring and understanding antibiotic resistance and the ecological dynamics of pathogens within both human and animal populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES241

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES241
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES241 genome assembly,

Gene Summary

Adenine Count

1178686 bp

Thymine Count

1175379 bp

Guanine Count

1569060 bp

Cytosine Count

1589634 bp

Genome Length

5512759 bp

Protein-coding Genes

4900 genes

Non-Coding Genes

358 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
glutamine amidotransferase class-iSAMEA3649557_01072Not AvailablePositive1125933 - 112667026879.0
pyrroloquinoline quinone biosynthesis protein f-like proteinSAMEA3649557_01073Not AvailableNegative1126667 - 112895283802.8
coenzyme pqq synthesis protein eSAMEA3649557_01074Not AvailableNegative1128952 - 113009442916.1
coenzyme pqq synthesis protein dSAMEA3649557_01075Not AvailableNegative1130081 - 113035910436.5
coenzyme pqq synthesis protein cSAMEA3649557_01076Not AvailableNegative1130362 - 113111728988.4
coenzyme pqq synthesis protein bSAMEA3649557_01077Not AvailableNegative1131111 - 113203733466.8
microsomal dipeptidaseSAMEA3649557_01078Not AvailableNegative1132300 - 113331937454.6
putative epoxide hydrolase proteinSAMEA3649557_01079Not AvailablePositive1133563 - 113455536235.8
ompr family transcriptional regulatory proteinSAMEA3649557_01080Not AvailablePositive1134642 - 113538228098.1
sensor histidine kinaseSAMEA3649557_01081Not AvailablePositive1135379 - 113672249304.6

Displaying genes 1401 – 1410 of 5258 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total