Klebsiella pneumoniae strain EuSCAPE_ES243

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES243 is a Gram-negative, rod-shaped bacterium characterized by its facultative anaerobic metabolism and chemoheterotrophic energy source. This strain can be found in various forms, including chains, pairs, and singles. It possesses flagella, which contribute to its mobility, and thrives optimally at 37°C within a mesophilic temperature range. K. pneumoniae EuSCAPE_ES243 is primarily associated with hosts such as Homo sapiens, Gallus gallus, and various other metazoans, including amphibians and mammals. This bacterium is free-living but has significant pathogenic potential in humans, responsible for a spectrum of serious health effects. These include bacteremia, urinary tract infections, pneumonia, and a range of other conditions such as sepsis and liver abscesses. The strain has been implicated in various infections, notably in vulnerable populations, including neonates, where it can cause early onset neonatal sepsis. The extensive list of health effects associated with K. pneumoniae highlights its role as an opportunistic pathogen, particularly in immunocompromised individuals or those with underlying health conditions. The presence of this strain in diverse host species suggests a complex ecological relationship, enabling it to adapt and thrive in different biological environments. This adaptability may contribute to the challenge of managing infections caused by K. pneumoniae, as it can persist across multiple hosts and environments, increasing its potential for transmission and resistance development.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES243

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES243
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES243 genome assembly,

Gene Summary

Adenine Count

1237289 bp

Thymine Count

1233180 bp

Guanine Count

1622179 bp

Cytosine Count

1598988 bp

Genome Length

5691636 bp

Protein-coding Genes

5087 genes

Non-Coding Genes

340 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
endoribonuclease l-pspSAMEA3649559_03278Not AvailableNegative3438903 - 343924712553.9
ding family atp-dependent helicase yoaaSAMEA3649559_03279Not AvailablePositive3439379 - 344128970244.9
metal-dependent protease molecular chaperoneSAMEA3649559_03280Not AvailablePositive3441435 - 344213024747.6
outer membrane protein slpSAMEA3649559_03281Not AvailablePositive3442169 - 344275020773.2
long-chain-fatty-acid--coa ligaseSAMEA3649559_03282Not AvailablePositive3442923 - 344464163630.1
ribonuclease dSAMEA3649559_03283Not AvailablePositive3444723 - 344583842089.5
cell division topological specificity factor mineSAMEA3649559_03284Not AvailableNegative3445915 - 344618410310.5
septum site-determining protein mindSAMEA3649559_03285Not AvailableNegative3446188 - 344700029660.8
septum formation inhibitorSAMEA3649559_03286Not AvailableNegative3447024 - 344772224918.0
protein ycglSAMEA3649559_03287Not AvailablePositive3447849 - 344813010824.1

Displaying genes 3471 – 3480 of 5427 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total