Klebsiella pneumoniae strain EuSCAPE_ES232

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES232 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. It typically resides in a host-associated environment, demonstrating a biotic relationship with various hosts, including Homo sapiens, Gallus gallus, and multiple other metazoan species. This strain is characterized by its mobility, attributed to the presence of flagella, and it can be found in different arrangements, including chains, pairs, and singles. It has an optimal growth temperature of 37°C and falls within the mesophilic temperature range. EuSCAPE_ES232 possesses a single replicon and is surrounded by two membranes, a characteristic feature of Gram-negative bacteria. Klebsiella pneumoniae is known for its pathogenic potential in humans, causing a wide array of health complications. These include bacteremia, urinary tract infections, pneumonia, and more severe conditions such as sepsis and meningitis. The strain's ability to infect various hosts highlights its adaptability and potential for zoonotic transmission. The ecological insight derived from the diverse host range of Klebsiella pneumoniae strain EuSCAPE_ES232 underlines its role as an opportunistic pathogen. Its presence in both human and animal hosts suggests that environmental factors and host interactions may significantly influence its pathogenicity and dissemination within ecosystems. Understanding these dynamics is crucial for developing effective strategies to control infections caused by this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES232

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES232
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES232 genome assembly,

Gene Summary

Adenine Count

1092265 bp

Thymine Count

1093871 bp

Guanine Count

1482756 bp

Cytosine Count

1483065 bp

Genome Length

5151957 bp

Protein-coding Genes

4617 genes

Non-Coding Genes

274 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
protein of uncharacterised function (duf2732)SAMEA3649548_00707Not AvailablePositive742254 - 7424878079.67
Dna adenine methylaseSAMEA3649548_00708Not AvailablePositive742478 - 74332931517.8
Replication protein aSAMEA3649548_00709Not AvailablePositive743326 - 74534776628.9
Hypothetical proteinSAMEA3649548_00710Not AvailableNegative745653 - 7459229764.01
Phage portal proteinSAMEA3649548_00711Not AvailableNegative745973 - 74702238974.3
Putative terminase atpase subunitSAMEA3649548_00712Not AvailableNegative747019 - 74879468029.3
Gpo family capsid scaffolding proteinSAMEA3649548_00713Not AvailablePositive748967 - 74976129796.9
Major capsid protein, p2 familySAMEA3649548_00714Not AvailablePositive749824 - 75084637933.9
Putative terminase endonuclease subunitSAMEA3649548_00715Not AvailablePositive750850 - 75155126504.5
Head completion/stabilization proteinSAMEA3649548_00716Not AvailablePositive751648 - 75210016129.2

Displaying genes 11 – 20 of 4891 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total