Klebsiella pneumoniae strain EuSCAPE_ES228

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES228 is a Gram-negative bacterium known for its pathogenicity in humans and other hosts. This organism exhibits a rod-shaped morphology and can be found in various arrangements, including chains, pairs, and singles. It is classified as a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, placing it in the mesophilic temperature range. K. pneumoniae strain EuSCAPE_ES228 is a chemoheterotroph, relying on organic compounds for energy. This bacterium possesses flagella, which contribute to its mobility, allowing it to navigate its host-associated habitats effectively. The strain is nonsporulating and has a single replicon with a characteristic double membrane structure. This strain is associated with a wide range of health effects, including but not limited to bacteremia, urinary tract infections, pneumonia, and various abdominal infections. Its pathogenicity extends beyond humans to include several other hosts such as birds (Gallus gallus, Phasianidae), mammals (Canis lupus familiaris, Sus scrofa, Equidae), and aquatic species (Danio rerio). This broad host range underscores the ecological adaptability of K. pneumoniae strain EuSCAPE_ES228. The ability of K. pneumoniae to cause severe infections in both humans and animals highlights its significance within clinical microbiology and public health. Understanding its characteristics and pathogenic potential is crucial for developing effective treatment and prevention strategies against infections, particularly in vulnerable populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES228

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES228
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES228 genome assembly,

Gene Summary

Adenine Count

1223783 bp

Thymine Count

1223696 bp

Guanine Count

1615781 bp

Cytosine Count

1636650 bp

Genome Length

5699910 bp

Protein-coding Genes

0 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Putative endo-n-neuraminidaseSAMEA3649544_00280Not AvailableNegative291887 - 29387571427.2
Tail fiber assembly proteinSAMEA3649544_00281Not AvailableNegative293868 - 29449122594.2
Tail fiber proteinSAMEA3649544_00282Not AvailableNegative294491 - 29523726021.3
Tail proteinSAMEA3649544_00283Not AvailableNegative295249 - 29590524362.8
Baseplate j proteinSAMEA3649544_00284Not AvailableNegative295902 - 29696337570.3
Hypothetical proteinSAMEA3649544_00285Not AvailableNegative296963 - 29731913138.9
Phage-related baseplate assembly protein gp45SAMEA3649544_00286Not AvailableNegative297385 - 29796621218.9
Mu-like prophage tail protein gppSAMEA3649544_00287Not AvailableNegative297950 - 29918845023.5
Tail/dna circulation proteinSAMEA3649544_00288Not AvailableNegative299172 - 30048547237.7
Tail length tape measure proteinSAMEA3649544_00289Not AvailableNegative300485 - 30262375619.8

Displaying genes 31 – 40 of 5404 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total