Klebsiella pneumoniae strain EuSCAPE_ES220

Klebsiella pneumoniae strain EuSCAPE_ES220 is a gram-negative, rod-shaped bacterium known for its pathogenic potential in humans and other hosts. It exhibits a facultative anaerobic metabolism, deriving energy as a chemoheterotroph. The strain can be found in various arrangements, including chains, pairs, and singles. Mobility is facilitated by the presence of flagella, and it thrives optimally at 37°C, within a mesophilic temperature range. This strain is associated with multiple health complications, notably bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its pathogenicity is significant, impacting not only humans (Homo sapiens) but also a diverse array of hosts including Gallus gallus (domestic chickens), Danio rerio (zebrafish), and various mammals like Canis lupus familiaris (domestic dogs) and Sus scrofa (domestic pigs). The extensive list of potential hosts reflects its adaptability and ecological versatility. EuSCAPE_ES220 is characterized by having a single replicon and a double membrane structure, typical of gram-negative bacteria. Notably, it does not form spores, indicating a reliance on other survival strategies in various environments. The free-living nature of this strain suggests it can thrive outside of host organisms, potentially contributing to its spread and the emergence of infections. The wide-ranging health effects associated with Klebsiella pneumoniae strain EuSCAPE_ES220 highlight its role as an opportunistic pathogen. Understanding its ecological relationships and pathogenic mechanisms is essential for developing strategies to mitigate its impact on human health and to control outbreaks in various host populations.