Klebsiella pneumoniae strain EuSCAPE_ES215

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES215 is a Gram-negative, facultative anaerobic bacterium that exhibits a rod shape and can be found in various arrangements, including chains, pairs, and singles. This strain is characterized as a chemoheterotroph, utilizing organic compounds for energy. With a mobility facilitated by flagella, EuSCAPE_ES215 thrives optimally at 37°C, making it well-suited for its host-associated habitat. This strain has been associated with a wide range of health effects in Homo sapiens, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its pathogenicity is significant, contributing to severe infections such as intra-abdominal infections, liver abscesses, and neonatal sepsis. The diverse array of hosts includes not only humans but also various animals, such as Gallus gallus (chickens), Canis lupus familiaris (domestic dogs), and Sus scrofa (pigs), indicating its ecological versatility. EuSCAPE_ES215 is a nonsporulating organism with a single replicon and a double membrane structure, typical of Gram-negative bacteria. Its free-living biotic relationship and ability to infect multiple hosts suggest a robust adaptability in various environments. This strain exemplifies the ecological and clinical significance of Klebsiella pneumoniae, highlighting its role as a formidable pathogen in both human and animal health. Its ability to cause various infections underlines the importance of monitoring and controlling its spread in clinical and agricultural settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES215

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES215
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES215 genome assembly,

Gene Summary

Adenine Count

1157197 bp

Thymine Count

1156417 bp

Guanine Count

1561802 bp

Cytosine Count

1547999 bp

Genome Length

5423415 bp

Protein-coding Genes

4885 genes

Non-Coding Genes

273 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
plasmid partition para proteinSAMEA3649531_04983Not AvailableNegative5244328 - 524505028226.3
amine oxidase, flavin-containingSAMEA3649531_04984Not AvailableNegative5245052 - 524631147186.1
oxidoreductaseSAMEA3649531_04985Not AvailableNegative5246308 - 524702725462.2
transcriptional regulatorSAMEA3649531_04986Not AvailableNegative5247024 - 524745816187.3
merr family regulatory proteinSAMEA3649531_04987Not AvailableNegative5247691 - 524841927498.6
outer membrane lipoprotein blcSAMEA3649531_04988Not AvailablePositive5248536 - 524906919819.6
cyanate transportSAMEA3649531_04989Not AvailableNegative5249079 - 524942612851.1
cobalt-zinc-cadmium resistance protein czcaSAMEA3649531_04990Not AvailableNegative5249499 - 5252648115124.0
cobalt/zinc/cadmium efflux rnd transporter, membrane fusion protein, czcb familySAMEA3649531_04991Not AvailableNegative5252660 - 525392245823.2
copper-binding proteinSAMEA3649531_04992Not AvailableNegative5253967 - 525431112215.8

Displaying genes 5011 – 5020 of 5158 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total