Klebsiella pneumoniae strain EuSCAPE_ES205

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_ES205 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. It is capable of existing in multiple cellular arrangements, including chains, pairs, and singles, and exhibits mobility due to the presence of flagella. This strain is mesophilic, with an optimal growth temperature of 37°C. K. pneumoniae EuSCAPE_ES205 is primarily host-associated, exhibiting a free-living biotic relationship with a diverse range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), various metazoans, Viridiplantae (plants), and several other animal species. This broad host range underscores its ecological versatility and potential for transmission across different species, including domesticated animals and wildlife. This strain is known for its pathogenicity in humans, causing a variety of severe health conditions such as bacteremia, urinary tract infections, pneumonia, and meningitis, among others. Its ability to cause infections in multiple organ systems highlights its significance as a human pathogen. K. pneumoniae's capacity for causing infections such as sepsis and pyogenic liver abscesses indicates a notable impact on public health, particularly in vulnerable populations. Understanding the ecology and pathogenic potential of strains like EuSCAPE_ES205 is crucial for developing strategies to manage and prevent infections attributed to this opportunistic pathogen.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_ES205

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_ES205
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_ES205 genome assembly,

Gene Summary

Adenine Count

1141592 bp

Thymine Count

1133647 bp

Guanine Count

1527862 bp

Cytosine Count

1545419 bp

Genome Length

5348520 bp

Protein-coding Genes

4896 genes

Non-Coding Genes

128 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
transmembrane proteinSAMEA3649521_01446Not AvailableNegative1522679 - 152428658121.8
putative urease accessory proteinSAMEA3649521_01447Not AvailableNegative1524440 - 152505721945.3
urease accessory protein urefSAMEA3649521_01448Not AvailableNegative1525066 - 152577626486.8
urease accessory protein ureeSAMEA3649521_01449Not AvailableNegative1525742 - 152621817501.9
urease subunit alphaSAMEA3649521_01450Not AvailableNegative1526228 - 152793160236.1
urease subunit betaSAMEA3649521_01451Not AvailableNegative1527924 - 152824411667.9
urease subunit gammaSAMEA3649521_01452Not AvailableNegative1528254 - 152855611087.6
urease accessory protein uredSAMEA3649521_01453Not AvailableNegative1528566 - 152939030184.7
acyl-phosphate:glycerol-3-phosphate o-acyltransferase plsySAMEA3649521_01454Not AvailableNegative1529788 - 153040522069.6
bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimeraseSAMEA3649521_01455Not AvailablePositive1530513 - 153089614093.8

Displaying genes 1501 – 1510 of 5024 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total