Klebsiella pneumoniae strain EuSCAPE_BU024

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BU024 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. As a chemoheterotroph, it derives energy from organic compounds, contributing to its versatility in various habitats, primarily associated with hosts. This strain is capable of movement, indicated by the presence of flagella, and typically forms chains, pairs, or exists as singles. The strain has a mesophilic temperature preference, with an optimal growth temperature of 37°C, making it well-suited for colonization in warm-blooded hosts. Klebsiella pneumoniae strain EuSCAPE_BU024 has been identified in a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other Metazoa, Viridiplantae, and domesticated animals, indicating its broad ecological niche. This strain is notably pathogenic to humans, associated with a range of serious health conditions, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its ability to cause diverse infections, such as liver abscesses and meningitis, underscores its clinical significance and the potential for severe health impacts. The presence of this strain in various hosts and its capacity to cause significant health issues highlight its importance in understanding microbial pathogenesis and the dynamics of host-associated bacteria. This adaptability and pathogenic potential suggest that Klebsiella pneumoniae strain EuSCAPE_BU024 plays a critical role in both human health and disease ecology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BU024

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BU024
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BU024 genome assembly,

Gene Summary

Adenine Count

1195000 bp

Thymine Count

1199609 bp

Guanine Count

1608940 bp

Cytosine Count

1586940 bp

Genome Length

5590489 bp

Protein-coding Genes

5067 genes

Non-Coding Genes

326 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lipoproteinSAMEA3538746_00904Not AvailablePositive955981 - 95660122189.7
sugar abc transporter atp-binding proteinSAMEA3538746_00905Not AvailablePositive956603 - 95814756784.1
ribose abc transporter permease rbscSAMEA3538746_00906Not AvailablePositive958165 - 95923237441.3
3-oxoacyl-acp reductaseSAMEA3538746_00907Not AvailablePositive959293 - 96009029225.8
short chain dehydrogenaseSAMEA3538746_00908Not AvailablePositive960291 - 96107627708.1
glutathione s-transferase, unnamed subgroup 2SAMEA3538746_00909Not AvailableNegative961129 - 96173422276.1
glycine cleavage system transcriptional activatorSAMEA3538746_00910Not AvailablePositive961989 - 96288232818.8
small-conductance mechanosensitive channelSAMEA3538746_00911Not AvailableNegative962879 - 96413547257.2
c-lysozyme inhibitorSAMEA3538746_00912Not AvailablePositive964360 - 96480615794.6
high-affinity choline uptake protein bettSAMEA3538746_00913Not AvailableNegative964852 - 96688575863.6

Displaying genes 1181 – 1190 of 5393 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total