Klebsiella pneumoniae strain EuSCAPE_HU053

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HU053 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. This strain typically resides in host-associated environments and exhibits mobility due to the presence of flagella. It is capable of forming chains, pairs, and singles in its cellular arrangement. EuSCAPE_HU053 is mesophilic, with an optimal growth temperature of 37°C, aligning with the typical human body temperature, which reflects its adaptation to living within various hosts. This strain has a singular replicon and is characterized by a dual membrane structure. Klebsiella pneumoniae is known for its significant health impacts on humans and a variety of other hosts, including domestic animals and plants. It can cause a range of serious infections, including bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections, among others. Some of the notable conditions associated with this strain include septicemia, neonatal sepsis, and liver abscesses. The presence of Klebsiella pneumoniae strain EuSCAPE_HU053 in diverse hosts, including Homo sapiens and various animal species, highlights its ecological versatility and potential for cross-species transmission. This adaptability underscores the importance of monitoring such strains in both clinical and environmental settings to mitigate their pathogenic risks and understand their role in microbial ecosystems.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HU053

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HU053
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HU053 genome assembly,

Gene Summary

Adenine Count

1173568 bp

Thymine Count

1171563 bp

Guanine Count

1544313 bp

Cytosine Count

1587080 bp

Genome Length

5476524 bp

Protein-coding Genes

4863 genes

Non-Coding Genes

320 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphoribosylaminoimidazole carboxylase atpase subunitSAMEA3538842_01884Not AvailablePositive2029806 - 203087339416.3
trna 2-selenouridine synthaseSAMEA3538842_01885Not AvailablePositive2030985 - 203206140432.4
outer membrane proteinSAMEA3538842_01886Not AvailableNegative2032169 - 203331443214.2
metabolite abc transporter in enterobacteriaceae, permease protein ec-ybbpSAMEA3538842_01887Not AvailableNegative2033496 - 203591088206.9
metabolite abc transporterSAMEA3538842_01888Not AvailableNegative2035907 - 203659324656.8
multifunctional acyl-coa thioesterase i and protease i and lysophospholipase l1SAMEA3538842_01889Not AvailablePositive2036594 - 203718722037.8
short chain dehydrogenaseSAMEA3538842_01890Not AvailablePositive2037216 - 203798627829.8
thioredoxin domain-containing protein ec-ybbnSAMEA3538842_01891Not AvailablePositive2038045 - 203889931775.8
ybbm seven transmembrane helix proteinSAMEA3538842_01892Not AvailableNegative2039007 - 203978928455.9
ybbl abc transporter atp-binding proteinSAMEA3538842_01893Not AvailableNegative2039776 - 204045325160.9

Displaying genes 2111 – 2120 of 5183 in total

Metabolites

1247 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1247 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total