Klebsiella pneumoniae strain EuSCAPE_HU050

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HU050 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, making it capable of thriving in both aerobic and anaerobic environments. This strain is classified as a chemoheterotroph, utilizing organic compounds for energy. The cells of EuSCAPE_HU050 can be found in various arrangements, including chains, pairs, and singles, and they possess flagella, indicating mobility. This strain is mesophilic, with an optimal growth temperature of 37°C, which aligns with the typical human body temperature, suggesting a close association with human hosts. EuSCAPE_HU050 is primarily found in host-associated habitats and has been identified in a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other Metazoa and plants. The pathogenicity of Klebsiella pneumoniae strain EuSCAPE_HU050 is significant, as it is linked to numerous health conditions, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. This strain does not form spores, and its pathogenic effects are predominantly observed in humans, highlighting its role in human health. The diverse range of hosts and the strain's ability to cause a variety of infections underline the ecological adaptability of Klebsiella pneumoniae. This adaptability may contribute to its transmission in both human and animal populations, emphasizing the importance of monitoring its presence in clinical and environmental settings to mitigate health risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HU050

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HU050
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HU050 genome assembly,

Gene Summary

Adenine Count

1215582 bp

Thymine Count

1212305 bp

Guanine Count

1607005 bp

Cytosine Count

1605536 bp

Genome Length

5640428 bp

Protein-coding Genes

5033 genes

Non-Coding Genes

232 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Baseplate assembly proteinSAMEA3538836_02439Not AvailablePositive2605006 - 260535612475.9
Baseplate assembly proteinSAMEA3538836_02440Not AvailablePositive2605358 - 260628133017.9
Tail proteinSAMEA3538836_02441Not AvailablePositive2606271 - 2609297107841.0
Hypothetical proteinSAMEA3538836_02442Not AvailablePositive2609294 - 26095068078.39
Tail fiber proteinSAMEA3538836_02443Not AvailablePositive2609506 - 261060338986.4
uncharacterised proteinSAMEA3538836_02444Not AvailableNegative2610757 - 261211552289.2
Tail proteinSAMEA3538836_02445Not AvailableNegative2612360 - 261285118182.8
Tail tape measure proteinSAMEA3538836_02446Not AvailableNegative2612867 - 2615842105324.0
Tail proteinSAMEA3538836_02447Not AvailableNegative2615987 - 261630411303.7
Major tail tube proteinSAMEA3538836_02448Not AvailableNegative2616350 - 261686518928.4

Displaying genes 81 – 90 of 5265 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total