Klebsiella pneumoniae strain EuSCAPE_HU036

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HU036 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. Its optimal growth temperature is 37°C, placing it within the mesophilic range. This strain is characterized by its mobility, attributed to the presence of flagella, and it typically exists in cell arrangements that include chains, pairs, and singles. This strain exhibits a significant biotic relationship as it is free-living yet associated with a wide variety of hosts, including Homo sapiens (humans), Gallus gallus (chickens), various metazoans, Viridiplantae (plants), Danio rerio (zebrafish), Ovis aries (sheep), Phasianidae (pheasants), Sus scrofa (pigs), Aves (birds), Canis lupus familiaris (domestic dogs), Amphibia (amphibians), and Equidae (horses). Klebsiella pneumoniae strain EuSCAPE_HU036 is known for its pathogenicity in humans, associated with a range of health effects. These include bacteremia, urinary tract infections, pneumonia, and various abdominal infections, among others. The strain is notable for its role in severe clinical conditions such as neonatal sepsis and septicemia. The ecological insight derived from the diverse host associations and pathogenic potential of Klebsiella pneumoniae strain EuSCAPE_HU036 underscores its adaptability and significance in both human health and the broader environment. This adaptability may contribute to its persistence in various ecological niches, thereby facilitating its transmission and impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HU036

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HU036
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HU036 genome assembly,

Gene Summary

Adenine Count

1201830 bp

Thymine Count

1200628 bp

Guanine Count

1604830 bp

Cytosine Count

1605755 bp

Genome Length

5613043 bp

Protein-coding Genes

5110 genes

Non-Coding Genes

184 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cro/ci family transcriptional regulatorSAMEA3538806_03941Not AvailablePositive4199923 - 420049220618.3
peptidase u32SAMEA3538806_03942Not AvailablePositive4200704 - 420266572827.2
protein of uncharacterised function (duf2554)SAMEA3538806_03943Not AvailableNegative4202678 - 42029088855.41
acid shock protein precursorSAMEA3538806_03944Not AvailableNegative4203058 - 420338411696.8
protein of uncharacterised function (duf2474)SAMEA3538806_03945Not AvailableNegative4203480 - 42036054552.96
cytochrome bd2, subunit iiSAMEA3538806_03946Not AvailableNegative4203605 - 420461536691.6
cytochrome bd2SAMEA3538806_03947Not AvailableNegative4204615 - 420601251569.5
uncharacterised proteinSAMEA3538806_03948Not AvailablePositive4206481 - 42065793734.88
gntr family transcriptional regulatorSAMEA3538806_03949Not AvailablePositive4206700 - 420811252580.4
abc transporter, periplasmic spermidine putrescine-binding protein potdSAMEA3538806_03950Not AvailablePositive4208417 - 420956242222.3

Displaying genes 4001 – 4010 of 5294 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total