Klebsiella pneumoniae strain EuSCAPE_HU036

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HU036 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. Its optimal growth temperature is 37°C, placing it within the mesophilic range. This strain is characterized by its mobility, attributed to the presence of flagella, and it typically exists in cell arrangements that include chains, pairs, and singles. This strain exhibits a significant biotic relationship as it is free-living yet associated with a wide variety of hosts, including Homo sapiens (humans), Gallus gallus (chickens), various metazoans, Viridiplantae (plants), Danio rerio (zebrafish), Ovis aries (sheep), Phasianidae (pheasants), Sus scrofa (pigs), Aves (birds), Canis lupus familiaris (domestic dogs), Amphibia (amphibians), and Equidae (horses). Klebsiella pneumoniae strain EuSCAPE_HU036 is known for its pathogenicity in humans, associated with a range of health effects. These include bacteremia, urinary tract infections, pneumonia, and various abdominal infections, among others. The strain is notable for its role in severe clinical conditions such as neonatal sepsis and septicemia. The ecological insight derived from the diverse host associations and pathogenic potential of Klebsiella pneumoniae strain EuSCAPE_HU036 underscores its adaptability and significance in both human health and the broader environment. This adaptability may contribute to its persistence in various ecological niches, thereby facilitating its transmission and impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HU036

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HU036
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HU036 genome assembly,

Gene Summary

Adenine Count

1201830 bp

Thymine Count

1200628 bp

Guanine Count

1604830 bp

Cytosine Count

1605755 bp

Genome Length

5613043 bp

Protein-coding Genes

5110 genes

Non-Coding Genes

184 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
protein ycar in kdo2-lipid a biosynthesis clusterSAMEA3538806_02369Not AvailablePositive2541107 - 25412896797.27
3-deoxy-manno-octulosonate cytidylyltransferaseSAMEA3538806_02370Not AvailablePositive2541286 - 254203227334.7
chromosome partition protein mukfSAMEA3538806_02371Not AvailablePositive2542169 - 254306234424.5
membrane proteinSAMEA3538806_02372Not AvailableNegative2543039 - 254381828255.5
putative metallothionein smtaSAMEA3538806_02373Not AvailablePositive2543940 - 254474030134.2
chromosome partition protein mukfSAMEA3538806_02374Not AvailablePositive2544737 - 254605950290.5
condesin subunit eSAMEA3538806_02375Not AvailablePositive2546040 - 254674427023.2
chromosome partition protein mukbSAMEA3538806_02376Not AvailablePositive2546744 - 2551192169539.0
l,d-transpeptidase ycbbSAMEA3538806_02377Not AvailablePositive2551393 - 255318365546.6
uncharacterised proteinSAMEA3538806_02378Not AvailableNegative2553120 - 25533358065.94

Displaying genes 2431 – 2440 of 5294 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total