Klebsiella pneumoniae strain EuSCAPE_HU022

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HU022 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe and a chemoheterotroph. This strain exhibits a diverse cellular arrangement, occurring in chains, pairs, and singles, and possesses flagella, enabling mobility. It has a mesophilic temperature range, with an optimal growth temperature of 37°C, which aligns with the human body temperature, suggesting its adaptation to host environments. This strain is associated with various hosts, including Homo sapiens, Gallus gallus, and several other metazoan species. The bacterium's pathogenicity in humans is notable, as it is linked to a wide range of health effects including bacteremia, urinary tract infections, pneumonia, and sepsis. Additional complications can arise from infections such as pyogenic liver abscesses and meningitis, highlighting its role as a significant opportunistic pathogen. Klebsiella pneumoniae strain EuSCAPE_HU022 has a single replicon and two membranes, characteristic of Gram-negative bacteria. Its biotic relationship is categorized as free-living, although its pathogenic potential is evident through its interactions with various hosts, indicating its ecological versatility. The strain's capacity to cause severe infections in humans and other animals emphasizes the importance of understanding its biology and ecology, particularly in the context of public health and the management of antibiotic resistance.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HU022

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HU022
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HU022 genome assembly,

Gene Summary

Adenine Count

1200122 bp

Thymine Count

1197278 bp

Guanine Count

1596535 bp

Cytosine Count

1610881 bp

Genome Length

5604816 bp

Protein-coding Genes

5078 genes

Non-Coding Genes

293 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
putative stress-response proteinSAMEA3538779_03814Not AvailableNegative4038416 - 40386258308.58
dna-damage-inducible sos response proteinSAMEA3538779_03815Not AvailableNegative4038860 - 404017647392.8
sos-response repressor and protease lexaSAMEA3538779_03816Not AvailableNegative4040246 - 404085422305.0
diacylglycerol kinaseSAMEA3538779_03817Not AvailableNegative4040977 - 404134513149.2
glycerol-3-phosphate acyltransferaseSAMEA3538779_03818Not AvailablePositive4041474 - 404389791326.8
4-hydroxybenzoate polyprenyltransferaseSAMEA3538779_03819Not AvailableNegative4043946 - 404481232388.2
chorismate-pyruvate lyaseSAMEA3538779_03820Not AvailableNegative4044825 - 404532218579.5
maltose regulon periplasmic proteinSAMEA3538779_03821Not AvailableNegative4045510 - 404643331991.7
maltoporinSAMEA3538779_03822Not AvailableNegative4046548 - 404783747779.0
maltose/maltodextrin transport atp-binding protein malkSAMEA3538779_03823Not AvailableNegative4047921 - 404903040645.5

Displaying genes 3991 – 4000 of 5371 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total