Klebsiella pneumoniae strain EuSCAPE_HU031

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HU031 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and chemoheterotroph. This strain is capable of existing in various forms, including chains, pairs, and singles, and possesses flagella, indicating its motility. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic temperature range. K. pneumoniae EuSCAPE_HU031 is primarily host-associated, with a broad spectrum of potential hosts that includes Homo sapiens, Gallus gallus, and various other vertebrates and invertebrates. Its biotic relationship is categorized as free-living, suggesting it can thrive independently in various environments, including within host organisms. This strain is significant in clinical settings due to its association with multiple health effects, such as bacteremia, urinary tract infections, pneumonia, and various other severe infections including neonatal sepsis and liver abscesses. The pathogenicity of K. pneumoniae EuSCAPE_HU031 in humans underlines its role as a notable opportunistic pathogen, particularly in immunocompromised individuals. Overall, the ecological versatility and pathogenic potential of K. pneumoniae EuSCAPE_HU031 highlight its importance in both environmental microbiology and public health. Understanding its interactions with diverse hosts and the mechanisms behind its pathogenicity can aid in addressing the challenges posed by infections it causes, especially in hospital settings where antibiotic resistance is a growing concern.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HU031

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HU031
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HU031 genome assembly,

Gene Summary

Adenine Count

1203031 bp

Thymine Count

1199695 bp

Guanine Count

1596020 bp

Cytosine Count

1616422 bp

Genome Length

5615168 bp

Protein-coding Genes

5091 genes

Non-Coding Genes

300 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
topoisomerase iv subunit aSAMEA3538793_03023Not AvailablePositive3194380 - 319663883652.2
1-acyl-sn-glycerol-3-phosphate acyltransferaseSAMEA3538793_03024Not AvailablePositive3196830 - 319756727267.5
cell division proteinSAMEA3538793_03025Not AvailablePositive3197651 - 319906351931.4
radical sam domain-containing proteinSAMEA3538793_03026Not AvailablePositive3199187 - 320137082329.2
acetyltransferaseSAMEA3538793_03027Not AvailablePositive3201428 - 320195520247.1
methylglyoxal reductaseSAMEA3538793_03028Not AvailableNegative3201991 - 320281830745.7
oxidoreductase yqhdSAMEA3538793_03029Not AvailableNegative3202964 - 320412742309.6
putative dna-binding transcriptional regulatorSAMEA3538793_03030Not AvailablePositive3204324 - 320522333698.1
deda family inner membrane protein yghbSAMEA3538793_03031Not AvailableNegative3205274 - 320593324038.4
cystathionine beta-lyaseSAMEA3538793_03032Not AvailableNegative3206065 - 320725243194.7

Displaying genes 3191 – 3200 of 5391 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total