Klebsiella pneumoniae strain EuSCAPE_HU031

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HU031 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and chemoheterotroph. This strain is capable of existing in various forms, including chains, pairs, and singles, and possesses flagella, indicating its motility. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic temperature range. K. pneumoniae EuSCAPE_HU031 is primarily host-associated, with a broad spectrum of potential hosts that includes Homo sapiens, Gallus gallus, and various other vertebrates and invertebrates. Its biotic relationship is categorized as free-living, suggesting it can thrive independently in various environments, including within host organisms. This strain is significant in clinical settings due to its association with multiple health effects, such as bacteremia, urinary tract infections, pneumonia, and various other severe infections including neonatal sepsis and liver abscesses. The pathogenicity of K. pneumoniae EuSCAPE_HU031 in humans underlines its role as a notable opportunistic pathogen, particularly in immunocompromised individuals. Overall, the ecological versatility and pathogenic potential of K. pneumoniae EuSCAPE_HU031 highlight its importance in both environmental microbiology and public health. Understanding its interactions with diverse hosts and the mechanisms behind its pathogenicity can aid in addressing the challenges posed by infections it causes, especially in hospital settings where antibiotic resistance is a growing concern.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HU031

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HU031
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HU031 genome assembly,

Gene Summary

Adenine Count

1203031 bp

Thymine Count

1199695 bp

Guanine Count

1596020 bp

Cytosine Count

1616422 bp

Genome Length

5615168 bp

Protein-coding Genes

5091 genes

Non-Coding Genes

300 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphoglycerate mutaseSAMEA3538793_01339Not AvailablePositive1386596 - 138724323869.4
right origin-binding proteinSAMEA3538793_01340Not AvailableNegative1387240 - 138810933330.1
crea proteinSAMEA3538793_01341Not AvailablePositive1388319 - 138879217154.8
dna-binding response regulator crebSAMEA3538793_01342Not AvailablePositive1388805 - 138949425776.4
two-component response regulator crecSAMEA3538793_01343Not AvailablePositive1389494 - 139091852424.4
inner membrane protein credSAMEA3538793_01344Not AvailablePositive1390979 - 139233750032.1
aerobic respiration control protein arcaSAMEA3538793_01345Not AvailableNegative1392400 - 139311627273.6
trmh family rna methyltransferaseSAMEA3538793_01346Not AvailablePositive1393749 - 139443525100.2
bifunctional aspartokinase i/homoserine dehydrogenase iSAMEA3538793_01347Not AvailablePositive1394797 - 139725988525.6
homoserine kinaseSAMEA3538793_01348Not AvailablePositive1397261 - 139819033251.2

Displaying genes 1591 – 1600 of 5391 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total