Klebsiella pneumoniae strain EuSCAPE_HU027

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HU027 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is characterized by its ability to form chains, pairs, and singles, and it possesses flagella, which contribute to its mobility. Its optimal growth temperature is 37°C, placing it within the mesophilic temperature range. The bacterium has a complex habitat, being host-associated and free-living, with a diverse array of hosts including Homo sapiens, Gallus gallus, various Metazoa, Viridiplantae, Danio rerio, Ovis aries, Phasianidae, Sus scrofa, Aves, Canis lupus familiaris, Amphibia, and Equidae. This broad host range indicates its ecological versatility and potential for transmission among different species. Klebsiella pneumoniae strain EuSCAPE_HU027 is associated with several serious health effects in humans, including bacteremia, urinary tract infections, pneumonia, and a variety of other infections such as cystitis, intra-abdominal infections, and meningitis. Its pathogenicity is significant, as it can lead to critical conditions like sepsis and neonatal sepsis. The presence of this strain within diverse biological systems highlights its role in both human health and disease ecology. Given its pathogenic potential and adaptability, monitoring its prevalence and antibiotic resistance patterns in clinical settings is crucial for public health management.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HU027

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HU027
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HU027 genome assembly,

Gene Summary

Adenine Count

1149930 bp

Thymine Count

1142901 bp

Guanine Count

1540425 bp

Cytosine Count

1550010 bp

Genome Length

5383266 bp

Protein-coding Genes

4876 genes

Non-Coding Genes

277 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
rossmann fold nucleotide-binding protein smfSAMEA3538786_04763Not AvailablePositive5018320 - 501944440482.9
uncharacterized protein conserved in bacteriaSAMEA3538786_04764Not AvailablePositive5019416 - 501988918561.3
dna topoisomerase type ia zn finger domain-containing proteinSAMEA3538786_04765Not AvailablePositive5019915 - 502045720052.3
putative ribosome maturation factorSAMEA3538786_04766Not AvailablePositive5020462 - 502103420717.6
shikimate 5-dehydrogenaseSAMEA3538786_04767Not AvailablePositive5021038 - 502185629087.9
protein of uncharacterised function (duf1488)SAMEA3538786_04768Not AvailablePositive5021853 - 50221109687.25
carbonic anhydrase, family 3SAMEA3538786_04769Not AvailableNegative5022086 - 502264020181.3
peptide transport system permease protein sapbSAMEA3538786_04770Not AvailableNegative5024007 - 502497235956.1
antimicrobial peptide abc transporter substrate-binding protein sapaSAMEA3538786_04771Not AvailableNegative5024969 - 502661261591.2
nucleoside-diphosphate-sugar epimeraseSAMEA3538786_04772Not AvailableNegative5026946 - 502785132057.0

Displaying genes 4821 – 4830 of 5153 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total