Klebsiella pneumoniae strain EuSCAPE_BU021

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_BU021 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. This strain exhibits a versatile cell arrangement, appearing in chains, pairs, and singles. It possesses flagella, enabling mobility, and thrives optimally at 37°C, fitting into a mesophilic temperature range. This bacterium is primarily host-associated, with a diverse array of potential hosts including Homo sapiens, various species of birds (Aves, Phasianidae), mammals (Canis lupus familiaris, Sus scrofa, Ovis aries), amphibians, and even plants (Viridiplantae). Such a wide-ranging host spectrum indicates its ecological adaptability and potential impact on different biological systems. Klebsiella pneumoniae strain EuSCAPE_BU021 is known for its pathogenicity in humans, associated with numerous health complications. It can cause serious conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The range of infections caused by this strain highlights its significance in clinical microbiology and public health. Despite its pathogenic potential, it is classified as free-living, suggesting that it can exist independently in various environments, although it has a notable association with host organisms. This dual nature of being both a pathogen and capable of free-living existence emphasizes the ecological importance of Klebsiella pneumoniae in microbial communities and its implications for disease transmission in humans and animals alike.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_BU021

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_BU021
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_BU021 genome assembly,

Gene Summary

Adenine Count

1353141 bp

Thymine Count

1356584 bp

Guanine Count

1745073 bp

Cytosine Count

1750157 bp

Genome Length

6204955 bp

Protein-coding Genes

5314 genes

Non-Coding Genes

334 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphate abc transporter permeaseSAMEA3538742_04474Not AvailableNegative4695704 - 469659432155.6
phosphate abc transporter permeaseSAMEA3538742_04475Not AvailableNegative4696594 - 469755334179.1
phosphate abc transporterSAMEA3538742_04476Not AvailableNegative4697682 - 469872236732.3
glucosamine--fructose-6-phosphate aminotransferaseSAMEA3538742_04477Not AvailableNegative4699059 - 470088866860.4
n-acetylglucosamine-1-phosphate uridyltransferaseSAMEA3538742_04478Not AvailableNegative4701072 - 470244249118.9
f0f1 atp synthase subunit epsilonSAMEA3538742_04479Not AvailableNegative4703139 - 470355815065.3
atp synthase subunit betaSAMEA3538742_04480Not AvailableNegative4703579 - 470496150213.4
atp synthase subunit gammaSAMEA3538742_04481Not AvailableNegative4704988 - 470585131515.3
atp synthase subunit alphaSAMEA3538742_04482Not AvailableNegative4705902 - 470744355172.3
f0f1 atp synthase subunit deltaSAMEA3538742_04483Not AvailableNegative4707456 - 470798919531.6

Displaying genes 4531 – 4540 of 5648 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total