Klebsiella pneumoniae strain EuSCAPE_HU013

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_HU013 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophic energy sources. It is capable of mobility, possessing flagella, and typically arranges itself in chains, pairs, or singles. This strain thrives optimally at 37°C, falling within the mesophilic temperature range. Ecologically, EuSCAPE_HU013 is primarily host-associated, indicating a significant relationship with various hosts, including Homo sapiens (humans) and a variety of other organisms such as Gallus gallus (chickens), Danio rerio (zebrafish), and several species of mammals and birds. This diverse host range underscores its adaptability and potential for transmission across different species. In terms of health impacts, Klebsiella pneumoniae strain EuSCAPE_HU013 is associated with a wide array of serious infections, including bacteremia, urinary tract infections, pneumonia, and meningitis, among others. The range of infections it can cause suggests a notable pathogenicity in humans, contributing to significant morbidity and, in some cases, mortality. The presence of only one replicon and two membranes in its cellular structure indicates its classification as a typical Gram-negative bacterium, which may influence its interactions with host immune systems and antibiotic resistance mechanisms. Overall, the versatility of Klebsiella pneumoniae strain EuSCAPE_HU013 in thriving in diverse habitats and its pathogenic potential highlights the need for ongoing surveillance and research to understand its role in both human health and environmental ecosystems.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_HU013

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_HU013
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_HU013 genome assembly,

Gene Summary

Adenine Count

1222852 bp

Thymine Count

1220426 bp

Guanine Count

1628231 bp

Cytosine Count

1624553 bp

Genome Length

5696062 bp

Protein-coding Genes

5163 genes

Non-Coding Genes

233 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
selenium-binding protein ydfzSAMEA3538765_04010Not AvailableNegative4280676 - 42808797280.84
mg2+ and co2+ transporterSAMEA3538765_04011Not AvailablePositive4281191 - 428221939204.6
cystathionine beta-lyaseSAMEA3538765_04012Not AvailableNegative4282233 - 428340543837.0
pts system proteinSAMEA3538765_04013Not AvailableNegative4283457 - 428504956539.5
maltose regulon regulatory protein maliSAMEA3538765_04014Not AvailablePositive4285222 - 428625036734.1
gtp-binding protein ydgaSAMEA3538765_04015Not AvailableNegative4286290 - 428779553509.2
mannose-6-phosphate isomeraseSAMEA3538765_04016Not AvailableNegative4287918 - 428909342397.8
fumarate hydratase class iSAMEA3538765_04017Not AvailablePositive4289295 - 429094159892.2
fumarate hydratase, class iiSAMEA3538765_04018Not AvailablePositive4291281 - 429268149851.1
dna replication terminus site-binding proteinSAMEA3538765_04019Not AvailableNegative4292671 - 429360335189.8

Displaying genes 4071 – 4080 of 5396 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total