Klebsiella pneumoniae strain EuSCAPE_HU012

Klebsiella pneumoniae strain EuSCAPE_HU012 is a pathogenic, Gram-negative bacterium classified as a chemoheterotroph. This versatile organism is capable of thriving in host-associated environments, demonstrating a facultative anaerobic lifestyle that allows it to adapt to varying oxygen levels. The bacteria exhibit a rod shape and can be observed in diverse arrangements, including chains, pairs, and singles. Mobility is facilitated by the presence of flagella. Optimal growth occurs at 37°C, placing EuSCAPE_HU012 within the mesophilic temperature range. The bacterium is characterized by having a single replicon and two membranes, which is consistent with its classification within the Enterobacteriaceae family. Klebsiella pneumoniae strain EuSCAPE_HU012 has a broad host range, including Homo sapiens, various livestock, and other vertebrates such as Gallus gallus (chickens) and Danio rerio (zebrafish). This wide host spectrum highlights its ecological versatility and ability to colonize diverse environments. Clinically, this strain is associated with a range of serious health issues in humans, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Its pathogenicity underscores the importance of understanding its biology and ecology, particularly in light of its significant health impact on both human and animal hosts. The presence of such a pathogenic strain in various hosts suggests potential zoonotic transmission routes, emphasizing the need for ongoing surveillance and research to mitigate its spread and associated health risks.